Review

Nature Clinical Practice Cardiovascular Medicine (2006) 3, 424-436
doi:10.1038/ncpcardio0613  
Received 19 August 2005 | Accepted 22 May 2006

Update on lipid-lowering therapy and LDL-cholesterol targets

Stephen D Wiviott* and Christopher P Cannon

Correspondence *The TIMI Study Group, Cardiovascular Division, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA

Email
 swiviott@partners.org

Despite LDL-cholesterol targets being lowered several times in recent years, are they low enough? New data continue to be published showing that LDL lowering should be a primary target of therapy, with the possibility of simultaneously raising HDL cholesterol. Wiviott and Cannon bring together the extensive data to provide an update.

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