Research Highlights

Nature Clinical Practice Cardiovascular Medicine (2006) 3, 236
doi:10.1038/ncpcardio0489  

Does prosthesis–patient mismatch affect outcome of aortic valve replacement?

Rebecca Ireland

This article has no abstract so we have provided the first paragraph of the full text.

Prosthesis–patient mismatch (PPM) occurs when a prosthetic aortic valve with a smaller effective orifice area (EOA) than that of the patient's native valve is implanted. PPM results in abnormally high transvalvular pressure gradients, but it is unclear whether postoperative survival is affected. Tasca et al. investigated the effect of PPM, defined as an INDEXED EOA, on overall out-of-hospital mortality and cardiac events after aortic valve replacement (AVR).

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