Atherothrombosis as a systemic, often silent, disease
Valentin Fuster and Pedro R Moreno
This article has no abstract so we have provided the first paragraph of the full text.
Atherothrombotic vascular disease (AVD) is a systemic, diffuse condition involving the coronary and peripheral arteries, and is the most common cause of death and disability worldwide. More than 25 million people in the US have at least one clinical manifestation of AVD, but in many more the disease remains silent harbinger of future cardiovascular events. Although AVD starts in infancy, manifestations are seen in adulthood as coronary artery disease (CAD), stroke and aortic, renal and peripheral vascular disease. Frequently, however, only one territory is symptomatic while the other regions remain clinically silent.
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