The role of shear stress in the generation of rupture-prone vulnerable plaques
CJ Slager*, JJ Wentzel, FJH Gijsen, JCH Schuurbiers, AC van der Wal, AFW van der Steen and PW Serruys
Correspondence *Biomedical Engineering, Thoraxcenter, EE 2322, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, the Netherlands
Email c.slager@erasmusmc.nl or
Email slager@scarlet.nl
Shear stress plays an essential part in the maintenance of healthy vessels. If risk factors for atherosclerosis are present, low shear stress can lead to abnormalities, possibly creating predilection sites for eccentric plaque growth. The role of shear stress in the development of plaque prone to rupture is explored.
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