Mechanisms, management and future directions for reperfusion injury after acute myocardial infarction
Richard O Cannon III
Correspondence National Heart, Lung, and Blood Institute, National Institutes of Health, Building 10-CRC, Room 5-3330, 10 Center Drive, Bethesda, MD 20892, USA
Email cannonr@nih.gov
Although a number of therapies have been able to reduce infarct size as part of reperfusion therapy in experimental studies, the clinical results after acute myocardial infarction have not been as satisfactory. Current understanding of the mechanisms and consequences of reperfusion injury and the pharmacologic options are discussed here.
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