Practice Point

Nature Clinical Practice Cardiovascular Medicine (2004) 1, 10-11
doi:10.1038/ncpcardio0005  
Received 9 July 2004 | Accepted 5 August 2004

Can cardiac-resynchronization therapy reduce mortality in patients suffering from advanced chronic heart failure?

John GF Cleland*, Justin Ghosh and Nick Freemantle

Correspondence *Academic Cardiology Unit, University of Hull, Castle Hill Hospital, Castle Road, Cottingham, Kingston upon Hull, HU16 5JQ, UK

Email
 J.G.Cleland@hull.ac.uk

This article has no abstract so we have provided the first paragraph of the full text.

The COMPANION trial findings suggest that CRT alone or combined with a defibrillator might reduce morbidity and mortality in patients with cardiac dys-synchrony and chronic heart failure (CHF). When viewed in isolation, however, the results are inconclusive and their interpretation for clinical practice problematic. This issue needs to be resolved by further large trials.1, 2

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