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News and Views
Nature 451, 638-639 (7 February 2008) | doi:10.1038/451638a; Published online 6 February 2008
Neuropathology: Alzheimer's in real time
Eliezer Masliah1
Abstract
A hallmark of Alzheimer's disease is the presence in the brain of protein deposits, or plaques, which are thought to form over a long period. But studies in mice suggest that the plaques can grow overnight.
Alzheimer's disease is the commonest neurodegenerative disorder in ageing human populations. It is characterized by memory loss and behavioural alterations in its early stages, and by severe cognitive impairment and dementia later on.
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