Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Case Report
  • Published:

Salvage prostate cryoablation after primary interstitial brachytherapy failure: a feasible approach

Prostate Cancer and Prostatic Diseases volume 9, pages 99–101 (2006)Cite this article

Abstract

Salvage treatment for recurrent prostate cancer remains a very difficult and challenging field in urologic oncology. The introduction of minimally invasive surgical procedures such a targeted cryoablation brings some hope with its feasibility and efficacy to become a potentially curable treatment. We present the case of a 75-year-old male with prostate cancer treated primarily by brachytherapy, who developed late locally recurrent disease that was successfully treated with targeted salvage cryoablation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1
Figure 2

Similar content being viewed by others

References

  1. Bianco FJ, Scardino PT, Stephenson AJ, Diblasco CJ, Fearn PA, Eastham JA . Long-term oncologic results of salvage radical prostatectomy for locally recurrent prostate cancer after radiotherapy. Int J Radiat Oncol Biol Phys 2005; 62: 448–453.

    Article  Google Scholar 

  2. Chen BT, Wood DP . Salvage prostatectomy in patients who have failed radiation therapy or cryotherapy as primary treatment for prostate cancer. Urology 2003; 62 (Suppl 1): 69–78.

    Article  Google Scholar 

  3. Amling CI, Lerner SE, Martin SK, Slezak JM, Blute ML, Zincke H . Deoxyribonucleic acid ploidy and serum prostate specific antigen predict outcome following salvage prostatectomy for radiation refractory prostate cancer. J Urol 1999; 161: 857–862.

    Article  CAS  Google Scholar 

  4. Touma NJ, Izawa JI, Chin JL . Current status of local salvage therapies following radiation failure for prostate cancer. J Urol 2005; 173: 373–379.

    Article  Google Scholar 

  5. Masterson TA, Stephenson AJ, Scardino PT, Eastham JA . Recovery of erectile function after salvage radical prostatectomy for locally recurrent prostate cancer after radiotherapy. Urology 2005; 66: 623–626.

    Article  Google Scholar 

  6. Sylvester J, Grimm P, Blasco J . The role of androgen ablation in patients with biochemical or local failure after definitive radiation therapy: A survey of practice patterns of urologists and radiation oncologists in the United States. Urology 2001; 58: 65–70.

    Article  CAS  Google Scholar 

  7. Bales GT, Williams MJ, Sinner M . Short-term outcomes after cryosurgical ablation of the prostate in men with recurrent prostate carcinoma following radiation therapy. Urology 1995; 46: 676–680.

    Article  CAS  Google Scholar 

  8. Corral DA, Pisters LL, von Eschenbach AC . Treatment options for localized recurrence of prostate cancer following radiation therapy. Urol Clin North Am 1996; 23: 677.

    Article  CAS  Google Scholar 

  9. Chin JL, Pautler SE, Mouraviev V, Touma N, Moore K, Downey DB . Results of salvage cryoablation of the prostate after radiation: identifying predictors of treatment failure and complications. J Urol 2001; 165: 1937–1941.

    Article  CAS  Google Scholar 

  10. Han KR, Cohen JK, Miller RJ, Pantuck AJ, Freitas DG, Cuevas CA et al. Treatment of organ confined prostate cancer with 3rd generation cryosurgery: preliminary multi-center experience. J Urol 2003; 170 (Part 1): 1126–1130.

    Article  Google Scholar 

  11. Katz AE, Prepelica KL, Masson P, Benson MC, McKiernan JM . Salvage cryosurgical ablation of the prostate (TCAP) for patients failing radiation: 10-year experience. Abstract book of AUA Annual Meeting, San Antonio, May, 21–26, J Urol 2005; 171 (Suppl 4): (#1662).

  12. Lam JS, Belldegrun AS . Salvage cryosurgery of the prostate after radiation failure. Rev Urol 2004; 6 (Suppl 4): S27–S36.

    PubMed  PubMed Central  Google Scholar 

  13. Cohen JK . Cryosurgery of the prostate: techniques and Indications. Rev Urol 2004; 6 (Suppl 4): S20–S26.

    PubMed  PubMed Central  Google Scholar 

  14. Anastasiadis AG, Sachdev R, Salomon L, Ghafar MA, Stisser BC, Snabsigh R et al. Comparison of health-related quality of life and prostate-associated symptoms after primary and salvage cryotherapy for prostate cancer. J Cancer Res Clin Oncol 2003; 129: 676–682.

    Article  Google Scholar 

  15. Horger DC, Clarke HS . Current status of cryosurgery in the treatment of prostate cancer. AUA Update Ser 2004; 23: 145–152.

    Google Scholar 

  16. Ahmed S, Davies J . Managing the complications of prostate cryosurgery. BJU Intl 2005; 96: 480–481.

    Article  Google Scholar 

  17. Ahmed S, Lindsey B, Davies J . Salvage cryosurgery for locally recurrent prostate cancer following radiotherapy. Prostate Cancer Prostatic Disease 2005; 8: 31–35.

    Article  CAS  Google Scholar 

Download references

Author information

Author notes

  1. T J Polascik: Research consultant for Oncura

Authors and Affiliations

  1. Division of Urologic Surgery and Duke Prostate Center (DPC), Department of Surgery, Duke University Medical Center, Durham, NC, USA

    V Mouraviev, B Evans & T J Polascik

Authors
  1. V Mouraviev
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. B Evans
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. T J Polascik
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to T J Polascik.

Additional information

Funding: None

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mouraviev, V., Evans, B. & Polascik, T. Salvage prostate cryoablation after primary interstitial brachytherapy failure: a feasible approach. Prostate Cancer Prostatic Dis 9, 99–101 (2006). https://doi.org/10.1038/sj.pcan.4500853

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.pcan.4500853

Keywords

Search

Advanced search

Quick links