Paper
Prostate Cancer and Prostatic Diseases (2005) 8, 210–214. doi:10.1038/sj.pcan.4500803; published online 10 May 2005
Switch from phytotherapy to tamsulosin in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH)
A J Gross1, M Busse2, J Leonard2 and H Schumacher2
- 1Marien Krankenhaus, Bergisch-Gladbach, Germany
- 2Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim am Rhein, Germany
Correspondence: AJ Gross, Marien Krankenhaus, Urological Center, Dr Robert Koch Str 18, 51465 Bergisch-Gladbach, Germany. E-mail: agross@mkh-bgl.de
Received 17 December 2004; Accepted 26 January 2005; Published online 10 May 2005.
Abstract
The aim of this observational prospective study was to evaluate the switch from phytotherapy to tamsulosin 0.4 mg once daily (o.d.) on efficacy, sexual function and tolerability in patients with lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH) who have a poor response to at least 4 weeks of phytotherapy. The switch to tamsulosin 0.4 mg o.d. improves LUTS and related quality of life. Sexual function is also slightly improved. Tamsulosin is as well tolerated as phytotherapy and abnormal ejaculation appears to be no problem. Tamsulosin is perceived by both patients and urologists to be superior to preceding phytotherapy.
Keywords:
benign prostatic hyperplasia, lower urinary tract symptoms, phytotherapy, tamsulosin, postmarketing surveillance study
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