Review

Prostate Cancer and Prostatic Diseases (2005) 8, 133–139. doi:10.1038/sj.pcan.4500781 Published online 15 February 2005

Nerve-sparing radical retropubic prostatectomy: techniques and clinical considerations

P Gontero1,2 and R S Kirby1,2

  1. 1Clinica Urologica, Università del Piemonte Orientale, Novara, Italy
  2. 2St Georges Hospital, London, UK

Correspondence: P Gontero, Clinica Urologica, Dipartimento di Scienze Mediche, Università del Piemonte Orientale, Via Solaroli, 17, 28100 Novara, Italy. E-mail: paolo.gontero@med.unipmn.it

Received 19 August 2004; Revised 1 November 2004; Accepted 1 December 2004; Published online 15 February 2005.

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Abstract

There are essentially two ways to accomplish nerve preservation during radical retropubic prostatectomy: the 'apical approach' described by Walsh and the so-called 'lateral approach', a simplified method where the dissection is initially conducted on the portion of the bundles that courses posterolateral to the prostate. Do the different techniques differ in the ability to preserve potency and in the positive surgical margins rate? No previous study has addressed this question. Above all, the preoperative and intraoperative indications to spare or not the nerves remain a matter of debate. The present review is an attempt to elucidate these questions in light of the current literature.

Keywords:

radical prostatectomy, nerve-sparing, techniques, surgical margins, erectile dysfunction

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