Prostate Cancer and Prostatic Diseases

FIGURE 1

FROM:

Patterns of protease production during prostate cancer progression: proteomic evidence for cascades in a transgenic model

R A Bok, E J Hansell, T P Nguyen, N M Greenberg, J H McKerrow and M A Shuman

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Figure 1.

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Gelatin zymography of tissues from normal C57BL/6 male mice (a) and from various tissues of advanced TRAMP males involved with tumor (b), including ventral prostate (VP), dorsal–lateral prostate (DLP), anterior prostate (AP), seminal vesicles (SV), lymph nodes (LN) of mesenteric (Mes), pelvic (Pel), and aortic (Aor) location, as well as gross primary tumor (Tum). Gelatin zymography of tissues from early and late TRAMP tissues: (c) isolated individual prostatic lobes from an early stage and late stage TRAMP male—AP, lateral prostate (LP), VP, dorsal prostate (DP), as well as SV; (d) side-by-side comparison of early and late TRAMP (TR) extracts from LP and SV. Additional samples from involved LNs are also shown.

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