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Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia: an ejaculation sparing technique

Prostate Cancer and Prostatic Diseases volume 12, pages 277–280 (2009)Cite this article

Abstract

This study examined efficacy and safety of the 980 nm side-firing diode laser operating at a power of 100 W in patients with lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH). Patients were selected for surgery on the basis of maximum urinary flow rate (Qmax) ⩽15 ml/s or transvesically measured post-voiding residual volume (PVR) >100 ml in conjunction with an International Prostate Symptom Score (IPSS) >7. Laser therapy was conducted under spinal anaesthesia. Qmax, IPSS, prostate volume, PVR, IPSS-Quality of Life (QoL) questionnaire and ejaculatory function were measured at baseline and at 1, 3, 6 and 12 months post-laser therapy. A total of 52 consecutive patients aged 52–65 years with mean (s.d.) prostate volume of 45.14 (9.15) g were treated. All patients were able to leave the hospital at a mean (s.d.) of 5 (2) h after the procedure. Mean (s.d.) follow-up was 100 (75.49) days. A significant reduction in IPPS was reported at 1 month (P<0.0001) and this was maintained through to 6 months. Significant durable improvements in Qmax, PVR and IPSS-QoL score were also reported for all patients (P<0.0001). No severe complications were reported, including any cases of urinary incontinence or significant irritative symptoms. None of the patients complained of a worsening of erectile function. This early experience in a pilot study with the 980 nm diode laser seems promising in the short-term and long-term outcome is being monitored.

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References

  1. Muntener M, Aelling S, Kuettel R, Gehrlach C, Sulser T, Strobel RT . Sexual function after transurethral resection of the prostate (TURP): results of an independent prospective multicentre assessment of outcome. Eur Urol 2007; 52: 510–515.

    Article  PubMed  Google Scholar 

  2. Rassweiler J, Teber D, Kuntz R, Hofmann R . Complications of transurethral resection of the prostate (TURP)-incidence, management, and prevention. Eur Urol 2006; 50: 969–979.

    Article  PubMed  Google Scholar 

  3. Costello AJ, Lusaya DG, Crowe HR . Transurethral laser ablation of the prostate: long-term results. World J Urol 1995; 13: 119–122.

    Article  CAS  PubMed  Google Scholar 

  4. Malek RS, Kuntzman RS, Barrett DM . Photoselective potassium-titanyl-phosphate laser vaporization of the benign obstructive prostate: observations on long-term outcomes. J Urol 2005; 174 (4 Part 1): 1344–1348.

    Article  PubMed  Google Scholar 

  5. Wendt-Nordahl G, Huckele S, Honeck P, Alken P, Knoll T, Michel MS et al. 980-nm Diode laser: a novel laser technology for vaporization of the prostate. Eur Urol 2007; 52: 1723–1728.

    Article  PubMed  Google Scholar 

  6. Seitz M, Sroka R, Gratzke C, Schlenker B, Schlenker B, Steinbrecher V et al. The diode laser: a novel side-firing approach for laser vaporisation of the human prostate—immediate efficacy and 1-year follow-up. Eur Urol 2007; 52: 1717–1722.

    Article  PubMed  Google Scholar 

  7. Muir G, Gómez Sancha F, Bachmann A, Choi B, Collins E, de la Rosette J et al. Techniques and training with Greenlight HPS 120-W laser therapy of the prostate: position paper. Eur Urol 2008; 7 (Suppl): 370–375.

    Article  Google Scholar 

  8. Bachmann A, Schürch L, Ruszat R, Wyler SF, Seifert HH, Müller A et al. Photoselective vaporization (PVP) versus transurethral resection of the prostate (TURP): a prospective bi-centre study of perioperative morbidity and early functional outcome. Eur Urol 2005; 48: 965–971.

    Article  PubMed  Google Scholar 

  9. Gilling PJ, Aho TF, Frampton CM, King CJ, Fraundorfer MR . Holmium laser enucleation of the prostate: results at 6 years. Eur Urol 2008; 53: 744–749.

    Article  PubMed  Google Scholar 

  10. Vavassori I, Hurle R, Vismara A, Manzetti A, Valenti S . Holmium laser enucleation of the prostate combined with mechanical morcellation: two years of experience with 196 patients. J Endourol 2004; 18: 109–112.

    Article  PubMed  Google Scholar 

  11. Ruszat R, Seitz M, Wyler SF, Lehmann K, Abe C, Bonkat G et al. GreenLight laser vaporization of the prostate: single-center experience and long-term results after 500 procedures. Eur Urol 2008; 54: 893–901.

    Article  PubMed  Google Scholar 

  12. Peterson MD, Matlaga BR, Kim SC, Lehmann K, Abe C, Bonkat G et al. Holmium laser enucleation of the prostate for men with urinary retention. J Urol 2005; 174: 998–1001.

    Article  PubMed  Google Scholar 

  13. Te AE, Malloy TR, Stein BS, Ulchaker JC, Nseyo UO, Hai MA et al. Photoselective vaporization of the prostate for the treatment of benign prostatic hyperplasia: 12-month results from the first United States multicenter prospective trial. J Urol 2004; 172 (4 Part 1): 1404–1408.

    Article  PubMed  Google Scholar 

  14. Meng F, Gao B, Fu Q, Chen J, Liu Y, Shi B et al. Change of sexual function in patients before and after Ho:YAG laser enucleation of the prostate. J Androl 2007; 28: 259–261.

    Article  PubMed  Google Scholar 

  15. Abdel-Khalek M, El-Hammady S, Ibrahiem el-H . A 4-year follow-up of a randomized prospective study comparing transurethral electrovaporization of the prostate with neodymium: YAG laser therapy for treating benign prostatic hyperplasia. BJU Int 2003; 91: 801–805.

    Article  CAS  PubMed  Google Scholar 

  16. Kabalin JN . Complications of laser treatment in urologic surgery. In: Taneja S, Smith RB, Ehrlich RM (eds). Complications of Urologic Surgery, 3rd edn, Elsevier: St Louis, MO, 2001.

    Google Scholar 

  17. Bachmann A, Ruszat R, Wyler S, Reich O, Seifert HH, Müller A et al. Photoselective vaporization of the prostate: the Basel experience after 108 procedures. Eur Urol 2005; 47: 798–804.

    Article  PubMed  Google Scholar 

  18. Kuntz RM, Ahyai S, Lehrich K, Fayad A . Transurethral holmium laser enucleation of the prostate versus transurethral electrocautery resection of the prostate: a randomized prospective trial in 200 patients. J Urol 2004; 172: 1012–1016.

    Article  PubMed  Google Scholar 

  19. Kuo R, Paterson R, Siqueira T, Watkins SL, Simmons GR, Steele RE et al. Holmium laser enucleation of the prostate: morbidity in a series of 206 patients. Urology 2003; 62: 59–63.

    Article  PubMed  Google Scholar 

  20. Sulser T, Reich O, Wyler S, Ruszat R, Casella R, Hofstetter A et al. Photoselective KTP laser vaporization of the prostate: first experiences with 65 procedures. J Endourol 2004; 18: 976–981.

    Article  PubMed  Google Scholar 

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  1. Department of Urology, Clinica Basile, Catania, Italy

    R Leonardi

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Correspondence to R Leonardi.

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Leonardi, R. Preliminary results on selective light vaporization with the side-firing 980 nm diode laser in benign prostatic hyperplasia: an ejaculation sparing technique. Prostate Cancer Prostatic Dis 12, 277–280 (2009). https://doi.org/10.1038/pcan.2009.5

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