Review

Prostate Cancer and Prostatic Diseases (2008) 11, 237–240; doi:10.1038/pcan.2008.9; published online 25 March 2008

State-of-the-art: prostate LDR brachytherapy

S Voulgaris1, J P Nobes2, R W Laing2 and S E M Langley1

  1. 1Department of Urology, St Luke's Cancer Centre, Royal Surrey County Hospital, Guildford, Surrey, UK
  2. 2Department of Clinical Oncology, St Luke's Cancer Centre, Royal Surrey County Hospital, Guildford, Surrey, UK

Correspondence: Dr S Voulgaris, Department of Urology, St Luke's Cancer Centre, Royal Surrey County Hospital, Guildford, Surrey GU2 5XX, UK. E-mail: bstelios@doctor.com

Received 23 September 2007; Accepted 23 October 2007; Published online 25 March 2008.

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Abstract

This article on low dose rate (LDR) prostate brachytherapy reviews long-term results, patient selection and quality of life issues. Mature results from the United States and United Kingdom are reported and issues regarding definitions of biochemical failure are discussed. Latest data comparing brachytherapy with radical prostatectomy or no definitive treatment and also the risk of secondary malignancies after prostate brachytherapy are presented. Urological parameters of patient selection and quality of life issues concerning urinary, sexual and bowel function are reviewed. The position of prostate brachytherapy next to surgery as a first-line treatment modality is demonstrated.

Keywords:

brachytherapy, results, quality of life, patient selection

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