Original Article

Prostate Cancer and Prostatic Diseases (2008) 11, 198–202; doi:10.1038/sj.pcan.4500983; published online 22 May 2007

Long-term outcome for lymph node-positive prostate cancer

G P Swanson1, M W Riggs2 and M Herman3

  1. 1The Departments of Radiation Oncology and Urology, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
  2. 2Department of Mathematics, Abilene Christian University, Abilene, TX, USA
  3. 3Department of Urology, Scott and White Memorial Hospital and Clinic, Temple, TX, USA

Correspondence: Dr GP Swanson, The Departments of Radiation Oncology and Urology, The University of Texas Health Science Center San Antonio, 7703 Floyd Curl Drive, MC 7889, San Antonio, TX 78229, USA. E-mail: gswanson@ctrc.net

Received 12 February 2007; Revised 20 April 2007; Accepted 20 April 2007; Published online 22 May 2007.

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Abstract

Although the number of men with lymph node-positive prostate cancer has declined, it is still significant and the challenge remains on how best to treat these patients. Only long-term follow-up can give a true indication of the outcome in prostate cancer. We evaluated our experience in treating lymph node-positive prostate cancer with a median follow-up of 10.2 years. The overall 5-year survival was 78% and the 10-year survival was 56% . Length of tumor control depends on the type of treatment given. Adding androgen ablation improves the duration of control dramatically, although optimal timing is still uncertain.

Keywords:

lymph node positive, prostatectomy, radiation, androgen ablation

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