Welcome to Oncogenesis!

Oncogenesis is a peer-reviewed open access online journal that publishes full-length papers, reviews, and short communications exploring the molecular basis of cancer and related phenomena. It seeks to promote diverse and integrated areas of molecular biology, cell biology, oncology, and genetics.

Oncogenesis recently received an Impact Factor of 4.143 *
*2015 Journal Citation Reports® (Thomson Reuters, 2016)

Submit to Oncogenesis and benefit from:

  • Wide visibility for your research through open access publication
  • Online submission and prompt publication times
  • Global exposure through nature.com to a wide audience

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Volume 6,
July 2017

ISSN (online): 2157-9024

2016 Impact Factor 4.143*
62/217 Oncology

Editor-in-Chief: Jan Paul Medema, Netherlands

*2016 Journal Citation Reports® Science Edition (Clarivate Analytics, 2017)


Read our latest web focus on 'Cancer and Metabolism'
While extremely diverse in origin, all cancer cells show profound metabolic changes. In this web focus on "Cancer & Metabolism" we present five reviews each discussing a special aspect of the connection between cancer cells and their metabolic adaptations, from molecular mechanisms to anticancer therapies, and highlighting the dialogue between whole organism and cancer cells (diets and cachexia). The collection also includes a number of other relevant articles from Oncogenesis and Oncogene.

Thank you to our reviewers
We would like to thank all those who took the time to review for Oncogenesis in 2015. The journal could not exist without the knowledge and critical evaluation that our reviewers provide. Your generosity is much appreciated, and we hope your association with the journal continues in future. Please check the list of reviewers in full.

The authors of a recent article in Oncogenesis present an interactive and comprehensive map of molecular mechanisms implicated in cancer and suggests several scenarios for application in cancer research, particularly for visualizing high-throughput data to innovative ways of exploring transcriptomes and phosphoproteomes.

A recent study in Oncogenesis reports a novel regulatory mechanism of metformin in prostate cancer cells which not only advances knowledge on the molecular mechanism of metformin but also provides a promising therapeutic strategy by targeting miR-708-5p and NNAT for prostate cancer treatment.


The Top Ten charts the articles that have been downloaded most often over the previous 30 days, in HTML and PDF format, from the Oncogenesis website. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.

July 2017

  1. Lipid metabolic reprogramming in cancer cells

    S Beloribi-Djefaflia, S Vasseur & F Guillaumond


    Abstract | Full Text | PDF

  2. Epigenetic and genetic features of 24 colon cancer cell lines

    D Ahmed, P W Eide, I A Eilertsen, S A Danielsen, M Eknæs, M Hektoen, G E Lind & R A Lothe


    Abstract | Full Text | PDF

  3. Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells

    A J Rice, E Cortes, D Lachowski, B C H Cheung, S A Karim, J P Morton & A del Río Hernández


    Abstract | Full Text | PDF

  4. Hypoxia and metabolic adaptation of cancer cells

    K L Eales, K E R Hollinshead & D A Tennant


    Abstract | Full Text | PDF

  5. Wnt signaling in triple-negative breast cancer

    SÖ-G Pohl, N Brook, M Agostino, F Arfuso, A P Kumar & A Dharmarajan


    Abstract | Full Text | PDF

  6. Urothelial cells undergo epithelial-to-mesenchymal transition after exposure to muscle invasive bladder cancer exosomes

    C A Franzen, R H Blackwell, V Todorovic, K A Greco, K E Foreman, R C Flanigan, P C Kuo & G N Gupta


    Abstract | Full Text | PDF

  7. Exosomes from Plasmodium-infected hosts inhibit tumor angiogenesis in a murine Lewis lung cancer model

    Y Yang, Q Liu, J Lu, D Adah, S Yu, S Zhao, Y Yao, L Qin, L Qin & X Chen


    Abstract | Full Text | PDF

  8. The Rho guanine nucleotide exchange factor ARHGEF5 promotes tumor malignancy via epithelial–mesenchymal transition

    Y Komiya, Y Onodera, M Kuroiwa, S Nomimura, Y Kubo, J-M Nam, K Kajiwara, S Nada, C Oneyama, H Sabe & M Okada


    Abstract | Full Text | PDF

  9. Understanding cachexia as a cancer metabolism syndrome

    P E Porporato


    Abstract | Full Text | PDF

  10. miR-200b inhibits proliferation and metastasis of breast cancer by targeting fucosyltransferase IV and α1,3-fucosylated glycans

    Q Zheng, X Cui, D Zhang, Y Yang, X Yan, M Liu, B Niang, F Aziz, S Liu, Q Yan & J Liu


    Abstract | Full Text | PDF

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21 July 2017

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