Oncogene TOP TEN

The top ten charts the articles that have been downloaded most often, in HTML format, from the Oncogene website in recent weeks. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.

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October 2009

  1. The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene FREE

    Y L Chua, Y Ito, J C M Pole, S Newman, S -F Chin, R C Stein, I O Ellis, C Caldas, M J O'Hare, A Murrell and P A W Edwards

    doi:10.1038/onc.2009.259

  2. Compartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones

    B H Kang and D C Altieri

    doi:10.1038/onc.2009.227

  3. Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis

    Y Li, X Ye, C Tan, J -A Hongo, J Zha, J Liu, D Kallop, M J C Ludlam and L Pei

    doi:10.1038/onc.2009.212

  4. Regulation of p53 expression, phosphorylation and subcellular localization by a G-protein-coupled receptor

    L Solyakov, E Sayan, J Riley, A Pointon and A B Tobin

    doi:10.1038/onc.2009.225

  5. 5q– myelodysplastic syndromes: chromosome 5q genes direct a tumor-suppression network sensing actin dynamics

    K M Eisenmann, K J Dykema, S F Matheson, N F Kent, A D DeWard, R A West, R Tibes, K A Furge and A S Alberts

    doi:10.1038/onc.2009.207

  6. Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer

    K S Kelly-Spratt, J Philipp-Staheli, K E Gurley, K Hoon-Kim, S Knoblaugh and C J Kemp

    doi:10.1038/onc.2009.226

  7. Ect2 links the PKCiota–Par6alpha complex to Rac1 activation and cellular transformation

    V Justilien and A P Fields

    doi:10.1038/onc.2009.217

  8. Rb2/p130 is the dominating pocket protein in the p53–p21 DNA damage response pathway leading to senescence

    H Helmbold, N Kömm, W Deppert and W Bohn

    doi:10.1038/onc.2009.222

  9. p53 responsive elements in human retrotransposons

    C R Harris, A DeWan, A Zupnick, R Normart, A Gabriel, C Prives, A J Levine and J Hoh

    doi:10.1038/onc.2009.246

  10. Yin Yang 1 regulates the transcriptional activity of androgen receptor

    Z Deng, M Wan, P Cao, A Rao, S D Cramer and G Sui

    doi:10.1038/onc.2009.231

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