ADVANCE ONLINE PUBLICATION

The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
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Reviews

August 18 2008

Critical pathways in cellular senescence and immortalization revealed by gene expression profiling

A L Fridman and M A Tainsky

Oncogene advance online publication, August 18, 2008; doi:10.1038/onc.2008.213

August 4 2008

Differences and evolution of the methods for the assessment of microsatellite instability

L Laghi, P Bianchi and A Malesci

Oncogene advance online publication, August 4, 2008; doi:10.1038/onc.2008.217

July 7 2008

Complementing mutations in core binding factor leukemias: from mouse models to clinical applications

A M S Müller, J Duque, J A Shizuru and M Lübbert

Oncogene advance online publication, July 7, 2008; doi:10.1038/onc.2008.196


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Original Articles

August 18 2008

Full-length hdmX transcripts decrease following genotoxic stress

M Markey and S J Berberich

Oncogene advance online publication, August 18, 2008; doi:10.1038/onc.2008.266


Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling

A Pen, M J Moreno, Y Durocher, P Deb-Rinker and D B Stanimirovic

Oncogene advance online publication, August 18, 2008; doi:10.1038/onc.2008.287

August 11 2008

Cyclin D1 in low-dose radiation-induced adaptive resistance

K M Ahmed, M Fan, D Nantajit, N Cao and J J Li

Oncogene advance online publication, August 11, 2008; doi:10.1038/onc.2008.265


Identification of IGFBP-6 as an effector of the tumor suppressor activity of SEMA3B

N Koyama, J Zhang,  Huqun, H Miyazawa, T Tanaka, X Su and K Hagiwara

Oncogene advance online publication, August 11, 2008; doi:10.1038/onc.2008.263


Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression

J Tang, X Yang and X Liu

Oncogene advance online publication, August 11, 2008; doi:10.1038/onc.2008.262

August 4 2008

Evidence for Hox and E2A–PBX1 collaboration in mouse T-cell leukemia

J Bijl, J Krosl, C-E Lebert-Ghali, J Vacher, N Mayotte and G Sauvageau

Oncogene advance online publication, August 4, 2008; doi:10.1038/onc.2008.233


Src family kinase oncogenic potential and pathways in prostate cancer as revealed by AZD0530 FREE

Y-M Chang, L Bai, S Liu, J C Yang, H-J Kung and C P Evans

Oncogene advance online publication, August 4, 2008; doi:10.1038/onc.2008.250


DNA-PKcs and ATM influence generation of ionizing radiation-induced bystander signals

R T Hagelstrom, K F Askin, A J Williams, L Ramaiah, C Desaintes, E H Goodwin, R L Ullrich and S M Bailey

Oncogene advance online publication, August 4, 2008; doi:10.1038/onc.2008.276


The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice

P Hasselblatt, L Gresh, H Kudo, J Guinea-Viniegra and E F Wagner

Oncogene advance online publication, August 4, 2008; doi:10.1038/onc.2008.211


PDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma

E Taniguchi, K Nishijo, A T McCleish, J E Michalek, M H Grayson, A J Infante, H E Abboud, R D Legallo, S J Qualman, B P Rubin and C Keller

Oncogene advance online publication, August 4, 2008; doi:10.1038/onc.2008.255


C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells

D Zhuang, S Mannava, V Grachtchouk, W-H Tang, S Patil, J A Wawrzyniak, A E Berman, T J Giordano, E V Prochownik, M S Soengas and M A Nikiforov

Oncogene advance online publication, August 4, 2008; doi:10.1038/onc.2008.258

July 28 2008

Poly(ADP-ribosyl)ation is implicated in the G0–G1 transition of resting cells

M Carbone, M N Rossi, M Cavaldesi, A Notari, P Amati and R Maione

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.221


E2f3a and E2f3b make overlapping but different contributions to total E2f3 activity

P S Danielian, L B Friesenhahn, A M Faust, J C West, A M Caron, R T Bronson and J A Lees

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.253


Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity

M De Luca, L Brunetto, I A Asteriti, M Giubettini, P Lavia and G Guarguaglini

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.252


Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway

Y Katsuno, A Hanyu, H Kanda, Y Ishikawa, F Akiyama, T Iwase, E Ogata, S Ehata, K Miyazono and T Imamura

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.232


PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigen

S Kotadia, L R Kao, S A Comerford, R T Jones, R E Hammer and T L Megraw

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.254


Lipocalin 2 is required for BCR-ABL-induced tumorigenesis

X Leng, H Lin, T Ding, Y Wang, Y Wu, S Klumpp, T Sun, Y Zhou, P Monaco, J Belmont, A Aderem, S Akira, R Strong and R Arlinghaus

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.209


MicroRNA-196a targets annexin A1: a microRNA-mediated mechanism of annexin A1 downregulation in cancers

R Luthra, R R Singh, M G Luthra, Y X Li, C Hannah, A M Romans, B A Barkoh, S S Chen, J Ensor, D M Maru, R R Broaddus, A Rashid and C T Albarracin

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.256


PRIMA-1MET induces mitochondrial apoptosis through activation of caspase-2

J Shen, H Vakifahmetoglu, H Stridh, B Zhivotovsky and K G Wiman

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.249


hPMC2 is required for recruiting an ERbeta coactivator complex to mediate transcriptional upregulation of NQO1 and protection against oxidative DNA damage by tamoxifen

S P Sripathy, L J Chaplin, N W Gaikwad, E G Rogan and M M Montano

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.235


Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins

K E Tagscherer, A Fassl, B Campos, M Farhadi, A Kraemer, B C Böck, S Macher-Goeppinger, B Radlwimmer, O D Wiestler, C Herold-Mende and W Roth

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.259


Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein

Y Takagi, T Kobayashi, M Shiono, L Wang, X Piao, G Sun, D Zhang, M Abe, Y Hagiwara, K Takahashi and O Hino

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.261


Pituitary tumor transforming gene 1 regulates Aurora kinase A activity

Y Tong, A Ben-Shlomo, C Zhou, K Wawrowsky and S Melmed

Oncogene advance online publication, July 28, 2008; doi:10.1038/onc.2008.234

July 21 2008

Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling

L E Dow, I A Elsum, C L King, K M Kinross, H E Richardson and P O Humbert

Oncogene advance online publication, July 21, 2008; doi:10.1038/onc.2008.219


Notch-dependent cell cycle arrest and apoptosis in mouse embryonic fibroblasts lacking Fbxw7

Y Ishikawa, I Onoyama, K I Nakayama and K Nakayama

Oncogene advance online publication, July 21, 2008; doi:10.1038/onc.2008.216


RASSF1A interacts with and activates the mitotic kinase Aurora-A

L Liu, C Guo, R Dammann, S Tommasi and G P Pfeifer

Oncogene advance online publication, July 21, 2008; doi:10.1038/onc.2008.220


Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype

K Mazan-Mamczarz, P R Hagner, S Corl, S Srikantan, W H Wood, K G Becker, M Gorospe, J D Keene, A S Levenson and R B Gartenhaus

Oncogene advance online publication, July 21, 2008; doi:10.1038/onc.2008.215


Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling

G Upadhyay, W Goessling, T E North, R Xavier, L I Zon and V Yajnik

Oncogene advance online publication, July 21, 2008; doi:10.1038/onc.2008.202

July 14 2008

Novel evidences for a tumor suppressor role of Rev3, the catalytic subunit of Pol zeta

J-M Brondello, M J Pillaire, C Rodriguez, P-A Gourraud, J Selves, C Cazaux and J Piette

Oncogene advance online publication, July 14, 2008; doi:10.1038/onc.2008.212


ABINs inhibit EGF receptor-mediated NF-kappaB activation and growth of EGF receptor-overexpressing tumour cells

L Huang, L Verstrepen, K Heyninck, A Wullaert, H Revets, P De Baetselier and R Beyaert

Oncogene advance online publication, July 14, 2008; doi:10.1038/onc.2008.208


Matrix metalloproteinase-11/stromelysin-3 exhibits collagenolytic function against collagen VI under normal and malignant conditions

E R Motrescu, S Blaise, N Etique, N Messaddeq, M-P Chenard, I Stoll, C Tomasetto and M-C Rio

Oncogene advance online publication, July 14, 2008; doi:10.1038/onc.2008.218

July 7 2008

Leukemogenic properties of NUP98-PMX1 are linked to NUP98 and homeodomain sequence functions but not to binding properties of PMX1 to serum response factor

K Hirose, C Abramovich, B Argiropoulos and R K Humphries

Oncogene advance online publication, July 7, 2008; doi:10.1038/onc.2008.210

June 30 2008

Recruitment of adenomatous polyposis coli and beta-catenin to axin-puncta

M C Faux, J L Coates, B Catimel, S Cody, A H A Clayton, M J Layton and A W Burgess

Oncogene advance online publication, June 30, 2008; doi:10.1038/onc.2008.205


Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription

R Fukuyama, R Niculaita, K P Ng, E Obusez, J Sanchez, M Kalady, P P Aung, G Casey and N Sizemore

Oncogene advance online publication, June 30, 2008; doi:10.1038/onc.2008.204


DAX1, a direct target of EWS/FLI1 oncoprotein, is a principal regulator of cell-cycle progression in Ewing's tumor cells

E García-Aragoncillo, J Carrillo, E Lalli, N Agra, G Gómez-López, Á Pestaña and J Alonso

Oncogene advance online publication, June 30, 2008; doi:10.1038/onc.2008.203


HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion

H Korkaya, A Paulson, F Iovino and M S Wicha

Oncogene advance online publication, June 30, 2008; doi:10.1038/onc.2008.207


TSPY and its X-encoded homologue interact with cyclin B but exert contrasting functions on cyclin-dependent kinase 1 activities

Y Li and Y-F Chris Lau

Oncogene advance online publication, June 30, 2008; doi:10.1038/onc.2008.206

June 23 2008

CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases

K Bettayeb, N Oumata, A Echalier, Y Ferandin, J A Endicott, H Galons and L Meijer

Oncogene advance online publication, June 23, 2008; doi:10.1038/onc.2008.191


Parkin as a tumor suppressor gene for hepatocellular carcinoma

M Fujiwara, H Marusawa, H-Q Wang, A Iwai, K Ikeuchi, Y Imai, A Kataoka, N Nukina, R Takahashi and T Chiba

Oncogene advance online publication, June 23, 2008; doi:10.1038/onc.2008.199


v-Src oncogene product increases sphingosine kinase 1 expression through mRNA stabilization: alteration of AU-rich element-binding proteins

S Sobue, M Murakami, Y Banno, H Ito, A Kimura, S Gao, A Furuhata, A Takagi, T Kojima, M Suzuki, Y Nozawa and T Murate

Oncogene advance online publication, June 23, 2008; doi:10.1038/onc.2008.198


PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia

G Xenaki, T Ontikatze, R Rajendran, I J Stratford, C Dive, M Krstic-Demonacos and C Demonacos

Oncogene advance online publication, June 23, 2008; doi:10.1038/onc.2008.192

June 16 2008

Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway

H F Horn and K H Vousden

Oncogene advance online publication, June 16, 2008; doi:10.1038/onc.2008.189


A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma

O Ndozangue-Touriguine, M Sebbagh, D Mérino, O Micheau, J Bertoglio and J Bréard

Oncogene advance online publication, June 16, 2008; doi:10.1038/onc.2008.197


Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells

L L Song, Y Peng, J Yun, P Rizzo, V Chaturvedi, S Weijzen, W M Kast, P J B Stone, L Santos, A Loredo, U Lendahl, G Sonenshein, B Osborne, J-Z Qin, A Pannuti, B J Nickoloff and L Miele

Oncogene advance online publication, June 16, 2008; doi:10.1038/onc.2008.190

June 9 2008

IKK/NF-kappaB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors

K Araki, K Kawauchi and N Tanaka

Oncogene advance online publication, June 9, 2008; doi:10.1038/onc.2008.184


Roles of induced expression of MAPK phosphatase-2 in tumor development in RET-MEN2A transgenic mice

T Hasegawa, A Enomoto, T Kato, K Kawai, R Miyamoto, M Jijiwa, M Ichihara, M Ishida, N Asai, Y Murakumo, K Ohara, Y Niwa, H Goto and M Takahashi

Oncogene advance online publication, June 9, 2008; doi:10.1038/onc.2008.182


Histone H2AX is a critical factor for cellular protection against DNA alkylating agents

J A Meador, M Zhao, Y Su, G Narayan, C R Geard and A S Balajee

Oncogene advance online publication, June 9, 2008; doi:10.1038/onc.2008.187


Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling

N M Reddy, S R Kleeberger, J H Bream, P G Fallon, T W Kensler, M Yamamoto and S P Reddy

Oncogene advance online publication, June 9, 2008; doi:10.1038/onc.2008.188


p300 provides a corepressor function by cooperating with YY1 and HDAC3 to repress c-Myc

N Sankar, S Baluchamy, R-K Kadeppagari, G Singhal, S Weitzman and B Thimmapaya

Oncogene advance online publication, June 9, 2008; doi:10.1038/onc.2008.181


LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII

M A Stutz, D L Shattuck, M B Laederich, K L Carraway III and C Sweeney

Oncogene advance online publication, June 9, 2008; doi:10.1038/onc.2008.185


Id1 immortalizes hematopoietic progenitors in vitro and promotes a myeloproliferative disease in vivo

H C Suh, W Leeanansaksiri, M Ji, K D Klarmann, K Renn, J Gooya, D Smith, I McNiece, S Lugthart, P J M Valk, R Delwel and J R Keller

Oncogene advance online publication, June 9, 2008; doi:10.1038/onc.2008.175


Involvement of elevated expression of multiple cell-cycle regulator, DTL/RAMP (denticleless/RA-regulated nuclear matrix associated protein), in the growth of breast cancer cells

T Ueki, T Nishidate, J H Park, M L Lin, A Shimo, K Hirata, Y Nakamura and T Katagiri

Oncogene advance online publication, June 9, 2008; doi:10.1038/onc.2008.186

June 2 2008

RNAi-mediated ERK2 knockdown inhibits growth of tumor cells in vitro and in vivo

A Bessard, C Frémin, F Ezan, A Fautrel, L Gailhouste and G Baffet

Oncogene advance online publication, June 2, 2008; doi:10.1038/onc.2008.163


DAPK2 is a novel E2F1/KLF6 target gene involved in their proapoptotic function

A Britschgi, E Trinh, M Rizzi, M Jenal, A Ress, A Tobler, M F Fey, K Helin and M P Tschan

Oncogene advance online publication, June 2, 2008; doi:10.1038/onc.2008.179


MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

F Fornari, L Gramantieri, M Ferracin, A Veronese, S Sabbioni, G A Calin, G L Grazi, C Giovannini, C M Croce, L Bolondi and M Negrini

Oncogene advance online publication, June 2, 2008; doi:10.1038/onc.2008.178


Constitutively active Rheb induces oncogenic transformation

H Jiang and P K Vogt

Oncogene advance online publication, June 2, 2008; doi:10.1038/onc.2008.180


E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines

M Kitagawa, M Aonuma, S H Lee, S Fukutake and F McCormick

Oncogene advance online publication, June 2, 2008; doi:10.1038/onc.2008.164


Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells

T Maimets, I Neganova, L Armstrong and M Lako

Oncogene advance online publication, June 2, 2008; doi:10.1038/onc.2008.166


Protein kinase C-theta regulates KIT expression and proliferation in gastrointestinal stromal tumors

W-b Ou, M-j Zhu, G D Demetri, C D M Fletcher and J A Fletcher

Oncogene advance online publication, June 2, 2008; doi:10.1038/onc.2008.177


Serine 28 phosphorylation of NRIF3 confers its co-activator function for estrogen receptor-alpha transactivation

A H Talukder, D-Q Li, B Manavathi and R Kumar

Oncogene advance online publication, June 2, 2008; doi:10.1038/onc.2008.151


Activation of NF-kappaB is required for mediating proliferative and antiapoptotic effects of progastrin on proximal colonic crypts of mice, in vivo

S Umar, S Sarkar, S Cowey and P Singh

Oncogene advance online publication, June 2, 2008; doi:10.1038/onc.2008.169

May 26 2008

Chfr interacts and colocalizes with TCTP to the mitotic spindle

A Burgess, J-C Labbé, S Vigneron, N Bonneaud, J M Strub, A Van Dorsselaer, T Lorca and A Castro

Oncogene advance online publication, May 26, 2008; doi:10.1038/onc.2008.167


Met-driven invasive growth involves transcriptional regulation of Arhgap12

A Gentile, L D'Alessandro, L Lazzari, B Martinoglio, A Bertotti, A Mira, L Lanzetti, P M Comoglio and E Medico

Oncogene advance online publication, May 26, 2008; doi:10.1038/onc.2008.173


Identification of SOX4 target genes using phylogenetic footprinting-based prediction from expression microarrays suggests that overexpression of SOX4 potentiates metastasis in hepatocellular carcinoma

Y-L Liao, Y-M Sun, G-Y Chau, Y-P Chau, T-C Lai, J-L Wang, J-T Horng, M Hsiao and A-P Tsou

Oncogene advance online publication, May 26, 2008; doi:10.1038/onc.2008.168


Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins

L Liu, L Chen, J Chung and S Huang

Oncogene advance online publication, May 26, 2008; doi:10.1038/onc.2008.137


Geldanamycin promotes premature mitotic entry and micronucleation in irradiated p53/p21 deficient colon carcinoma cells

D M Moran, G Gawlak, M S Jayaprakash, S Mayar and C G Maki

Oncogene advance online publication, May 26, 2008; doi:10.1038/onc.2008.172


Twist and p53 reciprocally regulate target genes via direct interaction

M Shiota, H Izumi, T Onitsuka, N Miyamoto, E Kashiwagi, A Kidani, G Hirano, M Takahashi, S Naito and K Kohno

Oncogene advance online publication, May 26, 2008; doi:10.1038/onc.2008.176


Mitochondrial redox signaling by p66Shc is involved in regulating androgenic growth stimulation of human prostate cancer cells

S Veeramani, T-C Yuan, F-F Lin and M-F Lin

Oncogene advance online publication, May 26, 2008; doi:10.1038/onc.2008.143


The MYCN oncogene is a direct target of miR-34a

J S Wei, Y K Song, S Durinck, Q-R Chen, A T C Cheuk, P Tsang, Q Zhang, C J Thiele, A Slack, J Shohet and J Khan

Oncogene advance online publication, May 26, 2008; doi:10.1038/onc.2008.154


Rb/E2F4 and Smad2/3 link survivin to TGF-beta-induced apoptosis and tumor progression

J Yang, K Song, T L Krebs, M W Jackson and D Danielpour

Oncogene advance online publication, May 26, 2008; doi:10.1038/onc.2008.165

May 19 2008

Roles of cyclins A and E in induction of centrosome amplification in p53-compromised cells

K Hanashiro, M Kanai, Y Geng, P Sicinski and K Fukasawa

Oncogene advance online publication, May 19, 2008; doi:10.1038/onc.2008.161


A 45-kDa ErbB3 secreted by prostate cancer cells promotes bone formation

S-H Lin, C-J Cheng, Y-C Lee, X Ye, W-W Tsai, J Kim, R Pasqualini, W Arap, N M Navone, S-M Tu, M Hu, L-Y Yu-Lee and C J Logothetis

Oncogene advance online publication, May 19, 2008; doi:10.1038/onc.2008.156


Inhibition of transcriptional activation and cell proliferation activities of adenovirus E1A by the unique N-terminal domain of CtBP2

L-J Zhao, T Subramanian and G Chinnadurai

Oncogene advance online publication, May 19, 2008; doi:10.1038/onc.2008.162

May 12 2008

Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links

J-B Bae, S S Mukhopadhyay, L Liu, N Zhang, J Tan, S Akhter, X Liu, X Shen, L Li and R J Legerski

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.139


The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling

M Chekenya, C Krakstad, A Svendsen, I A Netland, V Staalesen, B B Tysnes, F Selheim, J Wang, P Ø Sakariassen, T Sandal, P E Lønning, T Flatmark, P Ø Enger, R Bjerkvig, M Sioud and W B Stallcup

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.157


Overexpression of matrix metalloproteinase 1 in dermal fibroblasts from DNA repair-deficient/cancer-prone xeroderma pigmentosum group C patients

M Fréchet, E Warrick, C Vioux, O Chevallier, A Spatz, S Benhamou, A Sarasin, F Bernerd and T Magnaldo

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.153


Activation of BAG3 by Egr-1 in response to FGF-2 in neuroblastoma cells

A Gentilella, G Passiatore, S Deshmane, M C Turco and K Khalili

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.142


Identification and characterization of novel AML1-ETO fusion transcripts in pediatric t(8;21) acute myeloid leukemia: a report from the Children's Oncology Group

K M LaFiura, H Edwards, J W Taub, L H Matherly, J A Fontana, A N Mohamed, Y Ravindranath and Y Ge

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.134


Identification of ETS-like transcription factor 4 as a novel androgen receptor target in prostate cancer cells

H Makkonen, T Jääskeläinen, T Pitkänen-Arsiola, M Rytinki, K K Waltering, M Mättö, T Visakorpi and J J Palvimo

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.125


A nuclear role for Kaposi's sarcoma-associated herpesvirus-encoded K13 protein in gene regulation

H Matta, V Punj, S Schamus, L Mazzacurati, A M Chen, R Song, T Yang and P M Chaudhary

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.150


Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels

R Navab, C Pedraza, L Fallavollita, N Wang, E Chevet, P Auguste, S Jenna, Z You, A Bikfalvi, J Hu, R O'Connor, A Erickson, J S Mort and P Brodt

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.144


ErbB-2 inhibition activates Notch-1 and sensitizes breast cancer cells to a bold gamma-secretase inhibitor

C Osipo, P Patel, P Rizzo, A G Clementz, L Hao, T E Golde and L Miele

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.149


Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis

Q X Paulson, R V Pusapati, S Hong, R L Weaks, C J Conti and D G Johnson

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.138


Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells

M A Westhoff, S Zhou, M G Bachem, K M Debatin and S Fulda

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.148


The regulatory beta-subunit of protein kinase CK2 regulates cell-cycle progression at the onset of mitosis

C W Yde, B B Olsen, D Meek, N Watanabe and B Guerra

Oncogene advance online publication, May 12, 2008; doi:10.1038/onc.2008.146

May 5 2008

Oncogenic Ras upregulates NADPH oxidase 1 gene expression through MEK-ERK-dependent phosphorylation of GATA-6

Y Adachi, Y Shibai, J Mitsushita, W H Shang, K Hirose and T Kamata

Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.133


JunD is involved in the antiproliferative effect of Delta9-tetrahydrocannabinol on human breast cancer cells

M M Caffarel, G Moreno-Bueno, C Cerutti, J Palacios, M Guzman, F Mechta-Grigoriou and C Sanchez

Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.145


Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli

A P Kouzmenko, K Takeyama, Y Kawasaki, T Akiyama and S Kato

Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.127


Protein cysteine sulfinic acid reductase (sulfiredoxin) as a regulator of cell proliferation and drug response

K Lei, D M Townsend and K D Tew

Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.132


Intestinal tumor progression is promoted by decreased apoptosis and dysregulated Wnt signaling in Ceacam1 -/- mice

N Leung, C Turbide, B Balachandra, V Marcus and N Beauchemin

Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.136

April 28 2008

Cyclin D1 mediates resistance to apoptosis through upregulation of molecular chaperones and consequent redistribution of cell death regulators

G Roué, V Pichereau, H Lincet, D Colomer and B Sola

Oncogene advance online publication, April 28, 2008; doi:10.1038/onc.2008.126

April 21 2008

P21-activated kinase is required for mitotic progression and regulates Plk1

B Maroto, M B Ye, K von Lohneysen, A Schnelzer and U G Knaus

Oncogene advance online publication, April 21, 2008; doi:10.1038/onc.2008.131


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Short Communications

August 11 2008

The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition

M Shiono, T Kobayashi, R Takahashi, G Sun, M Abe, D Zhang, L Wang, X Piao, Y Takagi, R Mineki, H Taka, N Tada, S Sonobe, S Momose, M Ueda and O Hino

Oncogene advance online publication, August 11, 2008; doi:10.1038/onc.2008.283

August 4 2008

Heterozygous mutations in the tumor suppressor gene PATCHED provoke basal cell carcinoma-like features in human organotypic skin cultures

F Brellier, V Bergoglio, A Valin, S Barnay, O Chevallier-Lagente, P Vielh, A Spatz, P Gorry, M-F Avril and T Magnaldo

Oncogene advance online publication, August 4, 2008; doi:10.1038/o