ADVANCE ONLINE PUBLICATION
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
About advance online publication
April 28 2008 |
April 21 2008 |
April 14 2008 |
April 7 2008 |
March 31 2008 |
March 24 2008 |
March 17 2008 |
March 10 2008 |
March 3 2008 |
February 25 2008 |
February 18 2008 |
February 11 2008 |
February 4 2008 |
January 28 2008 |
January 21 2008 |
January 14 2008 |
December 17 2007 |
December 10 2007
May 5 2008
Original Articles
Oncogenic Ras upregulates NADPH oxidase 1 gene expression through MEK-ERK-dependent phosphorylation of GATA-6
Y Adachi, Y Shibai, J Mitsushita, W H Shang, K Hirose and T Kamata
Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.133
JunD is involved in the antiproliferative effect of 
9-tetrahydrocannabinol on human breast cancer cells
M M Caffarel, G Moreno-Bueno, C Cerutti, J Palacios, M Guzman, F Mechta-Grigoriou and C Sanchez
Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.145
NADPH oxidase 1 plays a critical mediating role in oncogenic Ras-induced vascular endothelial growth factor expression
D Komatsu, M Kato, J Nakayama, S Miyagawa and T Kamata
Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.102
Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli
A P Kouzmenko, K Takeyama, Y Kawasaki, T Akiyama and S Kato
Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.127
Protein cysteine sulfinic acid reductase (sulfiredoxin) as a regulator of cell proliferation and drug response
K Lei, D M Townsend and K D Tew
Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.132
Intestinal tumor progression is promoted by decreased apoptosis and dysregulated Wnt signaling in Ceacam1 - /- mice
N Leung, C Turbide, B Balachandra, V Marcus and N Beauchemin
Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.136
Short Communication
Overexpression of mRNA-binding protein CRD-BP in malignant melanomas
I Elcheva, R S Tarapore, N Bhatia and V S Spiegelman
Oncogene advance online publication, May 5, 2008; doi:10.1038/onc.2008.141
April 28 2008
Original Articles
Ceramide and raft signaling are linked with each other in UVA radiation-induced gene expression
S Grether-Beck, M Salahshour-Fard, A Timmer, H Brenden, I Felsner, R Walli, J Füllekrug and J Krutmann
Oncogene advance online publication, April 28, 2008; doi:10.1038/onc.2008.116
Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway
E E Hoskins, R W Gunawardena, K B Habash, T M Wise-Draper, M Jansen, E S Knudsen and S I Wells
Oncogene advance online publication, April 28, 2008; doi:10.1038/onc.2008.121
Adenovirus-mediated transfer of siRNA against MMP-2 mRNA results in impaired invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma
O Kargiotis, C Chetty, C S Gondi, A J Tsung, D H Dinh, M Gujrati, S S Lakka, A P Kyritsis and J S Rao
Oncogene advance online publication, April 28, 2008; doi:10.1038/onc.2008.122
Cyclin D1 mediates resistance to apoptosis through upregulation of molecular chaperones and consequent redistribution of cell death regulators
G Roué, V Pichereau, H Lincet, D Colomer and B Sola
Oncogene advance online publication, April 28, 2008; doi:10.1038/onc.2008.126
Pim kinase-dependent inhibition of c-Myc degradation
Y Zhang, Z Wang, X Li and N S Magnuson
Oncogene advance online publication, April 28, 2008; doi:10.1038/onc.2008.123
An antibody inhibitor of the LMO2-protein complex blocks its normal and tumorigenic functions
C-H Nam, M N Lobato, A Appert, L F Drynan, T Tanaka and T H Rabbitts
Oncogene advance online publication, April 28, 2008; doi:10.1038/onc.2008.130
Proteomic identification of p53-dependent protein phosphorylation
R Rahman-Roblick, U Hellman, S Becker, F G Bader, G Auer, K G Wiman and U J Roblick
Oncogene advance online publication, April 28, 2008; doi:10.1038/onc.2008.124
April 21 2008
Review
Multiple facets of junD gene expression are atypical among AP-1 family members
J M Hernandez, D H Floyd, K N Weilbaecher, P L Green and K Boris-Lawrie
Oncogene advance online publication, April 21, 2008; doi:10.1038/onc.2008.120
Original Articles
siRNA-mediated knockdown of Pdcd4 expression causes upregulation of p21(Waf1/Cip1) expression
N Bitomsky, N Wethkamp, R Marikkannu and K-H Klempnauer
Oncogene advance online publication, April 21, 2008; doi:10.1038/onc.2008.115
Matrix metalloproteinase-10 is a critical effector of protein kinase C
-Par6
-mediated lung cancer
L A Frederick, J A Matthews, L Jamieson, V Justilien, E A Thompson, D C Radisky and A P Fields
Oncogene advance online publication, April 21, 2008; doi:10.1038/onc.2008.119
Inhibition of Abl tyrosine kinase enhances nerve growth factor-mediated signaling in Bcr–Abl transformed cells via the alteration of signaling complex and the receptor turnover
A Koch, M Scherr, B Breyer, A Mancini, C Kardinal, K Battmer, M Eder and T Tamura
Oncogene advance online publication, April 21, 2008; doi:10.1038/onc.2008.107
P21-activated kinase is required for mitotic progression and regulates Plk1
B Maroto, M B Ye, K von Lohneysen, A Schnelzer and U G Knaus
Oncogene advance online publication, April 21, 2008; doi:10.1038/onc.2008.131
Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe
S M Sureban, S Ramalingam, G Natarajan, R May, D Subramaniam, K S Bishnupuri, A R Morrison, B K Dieckgraefe, D J Brackett, R G Postier, C W Houchen and S Anant
Oncogene advance online publication, April 21, 2008; doi:10.1038/onc.2008.97
Short Communications
The NMD mRNA surveillance pathway downregulates aberrant E-cadherin transcripts in gastric cancer cells and in CDH1 mutation carriers
R Karam, J Carvalho, I Bruno, C Graziadio, J Senz, D Huntsman, F Carneiro, R Seruca, M F Wilkinson and C Oliveira
Oncogene advance online publication, April 21, 2008; doi:10.1038/onc.2008.62
Epigenetic inactivation of the ERK inhibitor Spry2 in B-cell diffuse lymphomas
A Sánchez, F Setién, N Martinez, J L Oliva, M Herranz, M-F Fraga, M Alaminos, M Esteller and J M Rojas
Oncogene advance online publication, April 21, 2008; doi:10.1038/onc.2008.129
April 14 2008
Original Articles
FLASH acts as a co-activator of the transcription factor c-Myb and localizes to active RNA polymerase II foci
A H Alm-Kristiansen, T Sæther, V Matre, S Gilfillan, Ø Dahle and O S Gabrielsen
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.105
Regulation of IKK
by miR-199a affects NF-
B activity in ovarian cancer cells
R Chen, A B Alvero, D A Silasi, M G Kelly, S Fest, I Visintin, A Leiser, P E Schwartz, T Rutherford and G Mor
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.112
Methyl jasmonate binds to and detaches mitochondria-bound hexokinase
N Goldin, L Arzoine, A Heyfets, A Israelson, Z Zaslavsky, T Bravman, V Bronner, A Notcovich, V Shoshan-Barmatz and E Flescher
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.108
The transcription-repression domain of the adenovirus E1A oncoprotein targets p300 at the promoter
M Green, N K Panesar and P M Loewenstein
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.85
The BH3-only member Noxa causes apoptosis in melanoma cells by multiple pathways
M Hassan, A Alaoui, O Feyen, A Mirmohammadsadegh, F Essmann, A Tannapfel, E Gulbins, K Schulze-Osthoff and U R Hengge
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.90
Mechanistic insight into taxol-induced cell death
F Impens, P Van Damme, H Demol, J Van Damme, J Vandekerckhove and K Gevaert
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.96
Histone H4 lysine 20 monomethylation promotes transcriptional repression by L3MBTL1
N Kalakonda, W Fischle, P Boccuni, N Gurvich, R Hoya-Arias, X Zhao, Y Miyata, D MacGrogan, J Zhang, J K Sims, J C Rice and S D Nimer
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.67
BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models
D Li, L Ambrogio, T Shimamura, S Kubo, M Takahashi, L R Chirieac, R F Padera, G I Shapiro, A Baum, F Himmelsbach, W J Rettig, M Meyerson, F Solca, H Greulich and K-K Wong
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.109
CDK1 promotes cell proliferation and survival via phosphorylation and inhibition of FOXO1 transcription factor
P Liu, T P Kao and H Huang
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.104
Mycoplasma infection suppresses p53, activates NF-B and cooperates with oncogenic Ras in rodent fibroblast transformation
D Y Logunov, D V Scheblyakov, O V Zubkova, M M Shmarov, I V Rakovskaya, K V Gurova, N D Tararova, L G Burdelya, B S Naroditsky, A L Ginzburg and A V Gudkov
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.103
Unbalanced translocation, a major chromosome alteration causing loss of heterozygosity in human lung cancer
H Ogiwara, T Kohno, H Nakanishi, K Nagayama, M Sato and J Yokota
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.113
Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines
D Olmeda, A Montes, G Moreno-Bueno, J M Flores, F Portillo and A Cano
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.118
DICKKOPF-4 is induced by TCF/-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1,25-dihydroxyvitamin D3
N Pendás-Franco, J M García, C Peña, N Valle, H G Pálmer, M Heinäniemi, C Carlberg, B Jiménez, F Bonilla, A Muñoz and J M González-Sancho
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.88
Multiple pathways are involved in the anoxia response of SKIP3 including HuR-regulated RNA stability, NF-B and ATF4
T Rzymski, A Paantjens, J Bod and A L Harris
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.100
Evidence of functional interaction between NuMA-RAR and RXR in an in vivo model of acute promyelocytic leukemia
M A Sukhai, M Thomas, Y Xuan, L S A Chan, S A Hamadanizadeh, T Zhang, R R Bharadwaj, A C Schuh, R A Wells and S Kamel-Reid
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.106
Array CGH demonstrates characteristic aberration signatures in human papillary thyroid carcinomas governed by RET/PTC
K Unger, E Malisch, G Thomas, H Braselmann, A Walch, G Jackl, P Lewis, E Lengfelder, T Bogdanova, J Wienberg and H Zitzelsberger
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.99
PCDH8, the human homolog of PAPC, is a candidate tumor suppressor of breast cancer
J S Yu, S Koujak, S Nagase, C-M Li, T Su, X Wang, M Keniry, L Memeo, A Rojtman, M Mansukhani, H Hibshoosh, B Tycko and R Parsons
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.101
Short Communications
High-resolution, dual-platform aCGH analysis reveals frequent HIPK2 amplification and increased expression in pilocytic astrocytomas
H Deshmukh, T H Yeh, J Yu, M K Sharma, A Perry, J R Leonard, M A Watson, D H Gutmann and R Nagarajan
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.110
AID and RAG1 do not contribute to lymphomagenesis in E
c-myc transgenic mice
R M Nepal, A Zaheen, W Basit, L Li, S A Berger and A Martin
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.111
E2F1 regulates autophagy and the transcription of autophagy genes
S Polager, M Ofir and D Ginsberg
Oncogene advance online publication, April 14, 2008; doi:10.1038/onc.2008.117
April 7 2008
Review
Activated c-Abl tyrosine kinase in malignant solid tumors
J Lin and R Arlinghaus
Oncogene advance online publication, April 7, 2008; doi:10.1038/onc.2008.86
Original Articles
Loss of p53 induces epidermal growth factor receptor promoter activity in normal human keratinocytes
A Bheda, K E Creek and L Pirisi
Oncogene advance online publication, April 7, 2008; doi:10.1038/onc.2008.65
FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells
A N Cornforth, J S Davis, E Khanifar, K L Nastiuk and J J Krolewski
Oncogene advance online publication, April 7, 2008; doi:10.1038/onc.2008.80
Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy
S Finkin, Y Aylon, S Anzi, M Oren and E Shaulian
Oncogene advance online publication, April 7, 2008; doi:10.1038/onc.2008.77
AIP regulates stability of Aurora-A at early mitotic phase coordinately with GSK-3*
K Fumoto, P-C Lee, H Saya and A Kikuchi
Oncogene advance online publication, April 7, 2008; doi:10.1038/onc.2008.92
Cancer-specific enhancement of cisplatin-induced cytotoxicity with triptolide through an interaction of inactivated glycogen synthase kinase-3 with p53
Y Matsui, J Watanabe, M Ikegawa, T Kamoto, O Ogawa and H Nishiyama
Oncogene advance online publication, April 7, 2008; doi:10.1038/onc.2008.89
Short Communication
Loss of Rassf1a cooperates with Apc Min to accelerate intestinal tumourigenesis
L van der Weyden, M J Arends, O M Dovey, H L Harrison, G Lefebvre, N Conte, F V Gergely, A Bradley and D J Adams
Oncogene advance online publication, April 7, 2008; doi:10.1038/onc.2008.94
Oncogenomics
DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers
W W Lockwood, R Chari, B P Coe, L Girard, C MacAulay, S Lam, A F Gazdar, J D Minna and W L Lam
Oncogene advance online publication, April 7, 2008; doi:10.1038/onc.2008.98
Functional inactivation of the WTX gene is not a frequent event in Wilms' tumors
D Perotti, B Gamba, M Sardella, F Spreafico, M Terenziani, P Collini, A Pession, M Nantron, F Fossati-Bellani and P Radice
Oncogene advance online publication, April 7, 2008; doi:10.1038/onc.2008.93
March 31 2008
Review
Catch of the day: zebrafish as a human cancer model
K Stoletov and R Klemke
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.95
Original Articles
Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion
P Arora, B D Cuevas, A Russo, G L Johnson and J Trejo
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.84
EGFR somatic doublets in lung cancer are frequent and generally arise from a pair of driver mutations uncommonly seen as singlet mutations: one-third of doublets occur at five pairs of amino acids
Z Chen, J Feng, J-S Saldivar, D Gu, A Bockholt and S S Sommer
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.71
Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events
L De Boer, V Oakes, H Beamish, N Giles, F Stevens, M Somodevilla-Torres, C DeSouza and B Gabrielli
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.74
-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II
L-F Dong, P Low, J C Dyason, X-F Wang, L Prochazka, P K Witting, R Freeman, E Swettenham, K Valis, J Liu, R Zobalova, J Turanek, D R Spitz, F E Domann, I E Scheffler, S J Ralph and J Neuzil
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.69
The role of Nrf2 in increased reactive oxygen species and DNA damage in prostate tumorigenesis
D A Frohlich, M T McCabe, R S Arnold and M L Day
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.79
c-Myc and -catenin cooperate with loss of p53 to generate multiple members of the primitive neuroectodermal tumor family in mice
H Momota, A H Shih, M A Edgar and E C Holland
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.81
Epigenetic silencing of AXIN2/betaTrCP and deregulation of p53-mediated control lead to wild-type -catenin nuclear accumulation in lung tumorigenesis
R-C Tseng, R-K Lin, C-K Wen, C Tseng, H-S Hsu, W-H Hsu and Y-C Wang
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.83
Id-1 promotes chromosomal instability through modification of APC/C activity during mitosis in response to microtubule disruption
X Wang, K Di, X Zhang, H Y Han, Y C Wong, S C L Leung and M-T Ling
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.87
UVA radiation causes DNA strand breaks, chromosomal aberrations and tumorigenic transformation in HaCaT skin keratinocytes
K Wischermann, S Popp, S Moshir, K Scharfetter-Kochanek, M Wlaschek, F de Gruijl, W Hartschuh, R Greinert, B Volkmer, A Faust, A Rapp, P Schmezer and P Boukamp
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.70
Aurora A overexpression induces cellular senescence in mammary gland hyperplastic tumors developed in p53-deficient mice
D Zhang, T Shimizu, N Araki, T Hirota, M Yoshie, K Ogawa, N Nakagata, M Takeya and H Saya
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.76
Phosphoinositide 3-OH kinase p85 and p110 are essential for androgen receptor transactivation and tumor progression in prostate cancers
Q Zhu, H Youn, J Tang, O Tawfik, K Dennis, P F Terranova, J Du, P Raynal, J B Thrasher and B Li
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.91
Short Communications
Cdx1, a dispensable homeobox gene for gut development with limited effect in intestinal cancer
C Bonhomme, A Calon, E Martin, S Robine, A Neuville, M Kedinger, C Domon-Dell, I Duluc and J-N Freund
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.78
MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
Z Lu, M Liu, V Stribinskis, C M Klinge, K S Ramos, N H Colburn and Y Li
Oncogene advance online publication, March 31, 2008; doi:10.1038/onc.2008.72
March 24 2008
Original Articles
FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities
S Allerstorfer, G Sonvilla, H Fischer, S Spiegl-Kreinecker, C Gauglhofer, U Setinek, T Czech, C Marosi, J Buchroithner, J Pichler, R Silye, T Mohr, K Holzmann, B Grasl-Kraupp, B Marian, M Grusch, J Fischer, M Micksche and W Berger
Oncogene advance online publication, March 24, 2008; doi:10.1038/onc.2008.61
Threonine 74 of MOB1 is a putative key phosphorylation site by MST2 to form the scaffold to activate nuclear Dbf2-related kinase 1
S Hirabayashi, K Nakagawa, K Sumita, S Hidaka, T Kawai, M Ikeda, A Kawata, K Ohno and Y Hata
Oncogene advance online publication, March 24, 2008; doi:10.1038/onc.2008.66
Ribosomal protein S6 is a selective mediator of TRAIL-apoptotic signaling
Y-J Jeon, I K Kim, S-H Hong, H Nan, H-J Kim, H-J Lee, E S Masuda, O Meyuhas, B-H Oh and Y-K Jung
Oncogene advance online publication, March 24, 2008; doi:10.1038/onc.2008.73
Epstein–Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signaling
M Samanta, D Iwakiri and K Takada
Oncogene advance online publication, March 24, 2008; doi:10.1038/onc.2008.75
p73 and caspase-cleaved p73 fragments localize to mitochondria and augment TRAIL-induced apoptosis
A E Sayan, B S Sayan, V Gogvadze, D Dinsdale, U Nyman, T M Hansen, B Zhivotovsky, G M Cohen, R A Knight and G Melino
Oncogene advance online publication, March 24, 2008; doi:10.1038/onc.2008.64
Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death
N Tajeddine, L Galluzzi, O Kepp, E Hangen, E Morselli, L Senovilla, N Araujo, G Pinna, N Larochette, N Zamzami, N Modjtahedi, A Harel-Bellan and G Kroemer
Oncogene advance online publication, March 24, 2008; doi:10.1038/onc.2008.63
Short Communication
Pharmacological inhibition of c-Abl compromises genetic stability and DNA repair in Bcr-Abl-negative cells
S Fanta, M Sonnenberg, I Skorta, J Duyster, C Miething, W E Aulitzky and H van der Kuip
Oncogene advance online publication, March 24, 2008; doi:10.1038/onc.2008.68
March 17 2008
Original Articles
Deregulation of Cdk2 causes Bim-mediated apoptosis in p53-deficient tumors following actin damage
H D Chae, B M Kim, U J Yun and D Y Shin
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.46
Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy
G Eelen, I Vanden Bempt, L Verlinden, M Drijkoningen, A Smeets, P Neven, M R Christiaens, K Marchal, R Bouillon and A Verstuyf
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.51
A role for Myc in facilitating transcription activation by E2F1
J Y Leung, G L Ehmann, P H Giangrande and J R Nevins
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.55
Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2
H Nakamura, K Tanimoto, K Hiyama, M Yunokawa, T Kawamoto, Y Kato, K Yoshiga, L Poellinger, E Hiyama and M Nishiyama
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.58
NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells
W Qi, K Shakalya, A Stejskal, A Goldman, S Beeck, L Cooke and D Mahadevan
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.54
Axl promotes cell invasion by inducing MMP-9 activity through activation of NF-B and Brg-1
K-Y Tai, Y-S Shieh, C-S Lee, S-G Shiah and C-W Wu
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.57
p53-Mediated upregulation of DcR1 impairs oxaliplatin/TRAIL-induced synergistic anti-tumour potential in colon cancer cells
F Toscano, Z El Fajoui, F Gay, N Lalaoui, B Parmentier, J-A Chayvialle, J-Y Scoazec, O Micheau, J Abello and J-C Saurin
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.52
Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice
O Vasiljeva, M Korovin, M Gajda, H Brodoefel, L Boji
, A Krüger, U Schurigt, L Sevenich, B Turk, C Peters and T Reinheckel
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.59
Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors
I-C Wang, L Meliton, M Tretiakova, R H Costa, V V Kalinichenko and T V Kalin
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.60
Technical Report
Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish
D M Langenau, M D Keefe, N Y Storer, C A Jette, A C H Smith, C J Ceol, C Bourque, A T Look and L I Zon
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.56
Short Communications
Oncolytic herpes virus with defective ICP6 specifically replicates in quiescent cells with homozygous genetic mutations in p16
M Aghi, T Visted, R A DePinho and E A Chiocca
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.53
Targeted disruption of Aurora A causes abnormal mitotic spindle assembly, chromosome misalignment and embryonic lethality
K Sasai, J M Parant, M E Brandt, J Carter, H P Adams, S A Stass, A M Killary, H Katayama and S Sen
Oncogene advance online publication, March 17, 2008; doi:10.1038/onc.2008.47
March 10 2008
Original Articles
Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway
G Deep, N H Oberlies, D J Kroll and R Agarwal
Oncogene advance online publication, March 10, 2008; doi:10.1038/onc.2008.45
hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress
S C Gehen, R J Staversky, R A Bambara, P C Keng and M A O'Reilly
Oncogene advance online publication, March 10, 2008; doi:10.1038/onc.2008.48
VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation
J Huang and J Chen
Oncogene advance online publication, March 10, 2008; doi:10.1038/onc.2008.44
Retinoblastoma protein modulates gankyrin–MDM2 in regulation of p53 stability and chemosensitivity in cancer cells
W Qiu, J Wu, E M Walsh, Y Zhang, C-Y Chen, J Fujita and Z-Xj Xiao
Oncogene advance online publication, March 10, 2008; doi:10.1038/onc.2008.43
Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors
L S Steelman, P M Navolanic, M L Sokolosky, J R Taylor, B D Lehmann, W H Chappell, S L Abrams, E W T Wong, K M Stadelman, D M Terrian, N R Leslie, A M Martelli, F Stivala, M Libra, R A Franklin and J A McCubrey
Oncogene advance online publication, March 10, 2008; doi:10.1038/onc.2008.49
Cisplatin treatment increases survival and expansion of a highly tumorigenic side-population fraction by upregulating VEGF/Flt1 autocrine signaling
R Tsuchida, B Das, H Yeger, G Koren, M Shibuya, P S Thorner, S Baruchel and D Malkin
Oncogene advance online publication, March 10, 2008; doi:10.1038/onc.2008.38
Oncogenomics
Identification of unique and common low abundance tumour-specific transcripts by suppression subtractive hybridization and oligonucleotide probe array analysis
B H Liu, C H K Goh, L L P J Ooi and K M Hui
Oncogene advance online publication, March 10, 2008; doi:10.1038/onc.2008.50
March 3 2008
Review
Immune escape as a fundamental trait of cancer: focus on IDO
G C Prendergast
Oncogene advance online publication, March 3, 2008; doi:10.1038/onc.2008.35
Original Articles
The checkpoint kinases Chk1 and Chk2 regulate the functional associations between hBRCA2 and Rad51 in response to DNA damage
E M Bahassi, J L Ovesen, A L Riesenberg, W Z Bernstein, P E Hasty and P J Stambrook
Oncogene advance online publication, March 3, 2008; doi:10.1038/onc.2008.17
Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells
L Fleury, M Gerus, A C Lavigne, H Richard-Foy and K Bystricky
Oncogene advance online publication, March 3, 2008; doi