TABLE OF CONTENTS

Volume 28, Issue 4 (29 January 2009)

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Original Articles

A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations

A Takai, T Toyoshima, M Uemura, Y Kitawaki, H Marusawa, H Hiai, S Yamada, I M Okazaki, T Honjo, T Chiba and K Kinoshita

Oncogene 28: 469-478; advance online publication, November 10, 2008; doi:10.1038/onc.2008.415

Suppression of neuroblastoma growth by dipeptidyl peptidase IV: relevance of chemokine regulation and caspase activation

W T Arscott, A E LaBauve, V May and U V Wesley

Oncogene 28: 479-491; advance online publication, November 3, 2008; doi:10.1038/onc.2008.402

Hedgehog signaling promotes the degradation of tumor suppressor Sufu through the ubiquitin–proteasome pathway

S Yue, Y Chen and S Y Cheng

Oncogene 28: 492-499; advance online publication, November 10, 2008; doi:10.1038/onc.2008.403

Inhibition of pituitary tumors in Rb mutant chimeras through E2f4 loss reveals a key suppressive role for the pRB/E2F pathway in urothelium and ganglionic carcinogenesis

T Parisi, R T Bronson and J A Lees

Oncogene 28: 500-508; advance online publication, November 10, 2008; doi:10.1038/onc.2008.406

PTEN deficiency accelerates tumour progression in a mouse model of thyroid cancer

C J Guigon, L Zhao, M C Willingham and S-Y Cheng

Oncogene 28: 509-517; advance online publication, November 10, 2008; doi:10.1038/onc.2008.407

Disruption of the EGFR E884–R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity

Z Tang, S Jiang, R Du, E T Petri, A El-Telbany, P S O Chan, T Kijima, S Dietrich, K Matsui, M Kobayashi, S Sasada, N Okamoto, H Suzuki, K Kawahara, T Iwasaki, K Nakagawa, I Kawase, J G Christensen, T Hirashima, B Halmos, R Salgia, T J Boggon, J A Kern and P C Ma

Oncogene 28: 518-533; advance online publication, November 17, 2008; doi:10.1038/onc.2008.411

The uPA/uPAR system regulates the bioavailability of PDGF-DD: implications for tumour growth

M Ehnman, H Li, L Fredriksson, K Pietras and U Eriksson

Oncogene 28: 534-544; advance online publication, November 10, 2008; doi:10.1038/onc.2008.410

New p53 target, phosphatase of regenerating liver 1 (PRL-1) downregulates p53

S-H Min, D M Kim, Y-S Heo, Y-I Kim, H M Kim, J Kim, Y-M Han, I-C Kim and O-J Yoo

Oncogene 28: 545-554; advance online publication, November 10, 2008; doi:10.1038/onc.2008.409

Increased nucleotide polymorphic changes in the 5'-untranslated region of delta-catenin (CTNND2) gene in prostate cancer

T Wang, Y-H Chen, H Hong, Y Zeng, J Zhang, J-P Lu, B Jeansonne and Q Lu

Oncogene 28: 555-564; advance online publication, November 3, 2008; doi:10.1038/onc.2008.399

Regulation of the hTERT promoter activity by MSH2, the hnRNPs K and D, and GRHL2 in human oral squamous cell carcinoma cells

X Kang, W Chen, R H Kim, M K Kang and N-H Park

Oncogene 28: 565-574; advance online publication, November 17, 2008; doi:10.1038/onc.2008.404

Decreased BRCA1 confers tamoxifen resistance in breast cancer cells by altering estrogen receptor–coregulator interactions

J Wen, R Li, Y Lu and M A Shupnik

Oncogene 28: 575-586; advance online publication, November 10, 2008; doi:10.1038/onc.2008.405

Palladin contributes to invasive motility in human breast cancer cells

S M Goicoechea, B Bednarski, R García-Mata, H Prentice-Dunn, H J Kim and C A Otey

Oncogene 28: 587-598; advance online publication, November 3, 2008; doi:10.1038/onc.2008.408

Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway

R-S Chen, Y-M Song, Z-Y Zhou, T Tong, Y Li, M Fu, X-L Guo, L-J Dong, X He, H-X Qiao, Q-M Zhan and W Li

Oncogene 28: 599-609; advance online publication, November 17, 2008; doi:10.1038/onc.2008.414

Evaluation of the novel mitotic modulator ON 01910.Na in pancreatic cancer and preclinical development of an ex vivo predictive assay

A Jimeno, A Chan, G Cusatis, X Zhang, J Wheelhouse, A Solomon, F Chan, M Zhao, S C Cosenza, MV Ramana Reddy, M A Rudek, P Kulesza, R C Donehower, E P Reddy and M Hidalgo

Oncogene 28: 610-618; advance online publication, November 24, 2008; doi:10.1038/onc.2008.424

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Short Communication

Nitric oxide prodrug JS-K inhibits ubiquitin E1 and kills tumor cells retaining wild-type p53

J Kitagaki, Y Yang, J E Saavedra, N H Colburn, L K Keefer and A O Perantoni

Oncogene 28: 619-624; advance online publication, November 3, 2008; doi:10.1038/onc.2008.401

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