TABLE OF CONTENTS

Volume 28, Issue 3 (22 January 2009)

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Original Articles

Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy

P García-Maceira and J Mateo

Oncogene 28: 313-324; advance online publication, November 3, 2008; doi:10.1038/onc.2008.398

Crystal structure of a p53 core tetramer bound to DNA

K A Malecka, W C Ho and R Marmorstein

Oncogene 28: 325-333; advance online publication, November 3, 2008; doi:10.1038/onc.2008.400

Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62

J-P Pursiheimo, K Rantanen, P T Heikkinen, T Johansen and P M Jaakkola

Oncogene 28: 334-344; advance online publication, October 20, 2008; doi:10.1038/onc.2008.392

Sensitization of melanoma cells to TRAIL by UVB-induced and NF-kappaB-mediated downregulation of xIAP

B Thayaparasingham, A Kunz, N Peters and D Kulms

Oncogene 28: 345-362; advance online publication, November 3, 2008; doi:10.1038/onc.2008.397

Annexin A6 inhibits Ras signalling in breast cancer cells

S Vilá de Muga, P Timpson, L Cubells, R Evans, T E Hayes, C Rentero, A Hegemann, M Reverter, J Leschner, A Pol, F Tebar, R J Daly, C Enrich and T Grewal

Oncogene 28: 363-377; advance online publication, October 13, 2008; doi:10.1038/onc.2008.386

NRP/B mutations impair Nrf2-dependent NQO1 induction in human primary brain tumors

S Seng, H K Avraham, G Birrane, S Jiang, H Li, G Katz, C E Bass, R Zagozdzon and S Avraham

Oncogene 28: 378-389; advance online publication, November 3, 2008; doi:10.1038/onc.2008.396

The adenovirus E4orf4 protein induces growth arrest and mitotic catastrophe in H1299 human lung carcinoma cells

S Li, A Szymborski, M-J Miron, R Marcellus, O Binda, J N Lavoie and P E Branton

Oncogene 28: 390-400; advance online publication, October 27, 2008; doi:10.1038/onc.2008.393

Proteasome-mediated degradation of Tob is pivotal for triggering UV-induced apoptosis

T Suzuki, J Tsuzuku, K Kawakami, T Miyasaka and T Yamamoto

Oncogene 28: 401-411; advance online publication, October 13, 2008; doi:10.1038/onc.2008.387

The alpha-receptor for platelet-derived growth factor as a target for antibody-mediated inhibition of skeletal metastases from prostate cancer cells

M R Russell, W L Jamieson, N G Dolloff and A Fatatis

Oncogene 28: 412-421; advance online publication, October 13, 2008; doi:10.1038/onc.2008.390

A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition

A P Smith, A Verrecchia, G Fagà, M Doni, D Perna, F Martinato, E Guccione and B Amati

Oncogene 28: 422-430; advance online publication, November 3, 2008; doi:10.1038/onc.2008.395

Aggressiveness of HNSCC tumors depends on expression levels of cortactin, a gene in the 11q13 amplicon

E S Clark, B Brown, A S Whigham, A Kochaishvili, W G Yarbrough and A M Weaver

Oncogene 28: 431-444; advance online publication, October 20, 2008; doi:10.1038/onc.2008.389

Deacetylation of cortactin by SIRT1 promotes cell migration

Y Zhang, M Zhang, H Dong, S Yong, X Li, N Olashaw, P A Kruk, J Q Cheng, W Bai, J Chen, S V Nicosia and X Zhang

Oncogene 28: 445-460; advance online publication, October 13, 2008; doi:10.1038/onc.2008.388

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Short Communication

Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab

M Pickl and C H Ries

Oncogene 28: 461-468; advance online publication, November 3, 2008; doi:10.1038/onc.2008.394

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