FIGURE 7
FROM:
Cigarette smoke induces demethylation of prometastatic oncogene synuclein-
in lung cancer cells by downregulation of DNMT3B
H Liu, Y Zhou, S E Boggs, S A Belinsky and J Liu
BACK TO ARTICLEFigure 7.
Silencing SNCG expression by DNMT3B not by other DNMTs. H292 cells were transiently transfected with plasmid pcDNA-DNMT1, pcDNA-DNMT3A, pcDNA-DNMT3B or pcDNA3.1 empty vector (mock) individually. Three days posttransfection, cells were harvested and total lysates were prepared for Western blot analysis using anti-SNCG antibody. Overexpression of individual DNMTs in respectively transfected cells was confirmed by real-time RT–PCR analyses. The data shown represent three separate transfection experiments.
