TABLE OF CONTENTS

Volume 26, Issue 27 (7 June 2007)

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Original Articles

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

D Mahadevan, L Cooke, C Riley, R Swart, B Simons, K Della Croce, L Wisner, M Iorio, K Shakalya, H Garewal, R Nagle and D Bearss

Oncogene 26: 3909-3919; advance online publication, February 26, 2007; doi:10.1038/sj.onc.1210173

Selective inhibition of MEK1/2 reveals a differential requirement for ERK1/2 signalling in the regulation of HIF-1 in response to hypoxia and IGF-1

K M Sutton, S Hayat, N-M Chau, S Cook, J Pouyssegur, A Ahmed, N Perusinghe, R Le Floch, J Yang and M Ashcroft

Oncogene 26: 3920-3929; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210168

A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth

G Denning, B Jean-Joseph, C Prince, D L Durden and P K Vogt

Oncogene 26: 3930-3940; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210175

YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia

H-L Sun, Y-N Liu, Y-T Huang, S-L Pan, D-Y Huang, J-H Guh, F-Y Lee, S-C Kuo and C-M Teng

Oncogene 26: 3941-3951; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210169

Analysis of gene expression identifies PLAB as a mediator of the apoptotic activity of fenretinide in human ovarian cancer cells

V Appierto, M G Villani, E Cavadini, M Gariboldi, L De Cecco, M A Pierotti, J R Lambert, J Reid, P Tiberio, N Colombo and F Formelli

Oncogene 26: 3952-3962; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210171

Disparity of histone deacetylase inhibition on repair of radiation-induced DNA damage on euchromatin and constitutive heterochromatin compartments

T C Karagiannis, H Kn and A El-Osta

Oncogene 26: 3963-3971; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210174

'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737

X Lin, S Morgan-Lappe, X Huang, L Li, D M Zakula, L A Vernetti, S W Fesik and Y Shen

Oncogene 26: 3972-3979; advance online publication, December 18, 2006; doi:10.1038/sj.onc.1210166

DNA-PK phosphorylation sites on Oct-1 promote cell survival following DNA damage

C Schild-Poulter, A Shih, D Tantin, N C Yarymowich, S Soubeyrand, P A Sharp and R J G Haché

Oncogene 26: 3980-3988; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210165

DNA methylation and histone modification regulate silencing of epithelial cell adhesion molecule for tumor invasion and progression

K-Y Tai, S-G Shiah, Y-S Shieh, Y-R Kao, C-Y Chi, E Huang, H-S Lee, L-C Chang, P-C Yang and C-W Wu

Oncogene 26: 3989-3997; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210176

HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells

K M Mohankumar, X Q Xu, T Zhu, N Kannan, L D Miller, E T Liu, P D Gluckman, S Sukumar, B S Emerald and P E Lobie

Oncogene 26: 3998-4008; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210180

Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice

K A Loffler, C A Biondi, M G Gartside, M M Serewko-Auret, R Duncan, I D Tonks, A W Mould, P Waring, H K Muller, G F Kay and N K Hayward

Oncogene 26: 4009-4017; advance online publication, December 18, 2006; doi:10.1038/sj.onc.1210163

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Short Communications

Epigenetic patterns of the retinoic acid receptor beta 2 promoter in retinoic acid-resistant thyroid cancer cells

A Cras, D Darsin-Bettinger, N Balitrand, B Cassinat, A Soulié, M-E Toubert, L Delva and C Chomienne

Oncogene 26: 4018-4024; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210178

CLCP1 interacts with semaphorin 4B and regulates motility of lung cancer cells

H Nagai, N Sugito, H Matsubara, Y Tatematsu, T Hida, Y Sekido, M Nagino, Y Nimura, T Takahashi and H Osada

Oncogene 26: 4025-4031; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210183

Tumor promoting properties of the ETS protein MEF in ovarian cancer

J J Yao, Y Liu, H D Lacorazza, R A Soslow, J M Scandura, S D Nimer and C V Hedvat

Oncogene 26: 4032-4037; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210170

An optimal range of transcription potency is necessary for efficient cell transformation by c-Rel to ensure optimal nuclear localization and gene-specific activation

Y Fan and C Gélinas

Oncogene 26: 4038-4043; advance online publication, December 18, 2006; doi:10.1038/sj.onc.1210164

Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice

C Trapp, K Reite, A Klungland and B Epe

Oncogene 26: 4044-4048; advance online publication, January 8, 2007; doi:10.1038/sj.onc.1210167

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