Oncogene - Figure 3 for article: Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM

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Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM

Hiroyuki Tagawa, Sivasundaram Karnan, Ritsuro Suzuki, Keitaro Matsuo, Xiaohua Zhang, Akinobu Ota, Yasuo Morishima, Shigeo Nakamura and Masao Seto

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Figure 3.

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Genomic profiles of chromosome 2q from a patient sample (G468) and from three MCL cell lines (SP-53, Z-138 and Jeko-1). Log₂ ratio over +0.2 represents genomic copy number gain, and a log₂ ratio below -0.2 genomic copy number loss. Physical distances (Mb) from the 2q centromere are indicated. The vertical lines indicate the lowest locus of chromosome 2 at BAC438K19 containing the BIM gene. Log₂ ratios were -0.59 (G468), -2.75 (SP-53), -1.71 (Z-138) and -1.76 (Jeko-1) at BAC438K19, suggesting that homozygous loss occurs at the BIM gene locus

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FIGURE 3

Genome-wide array-based CGH for mantle cell lymphoma: identification of homozygous deletions of the proapoptotic gene BIM

Figure 3.