TABLE OF CONTENTS

Volume 24, Issue 4 (20 January 2005)

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Original Papers

The HTLV-I Tax oncoprotein targets the retinoblastoma protein for proteasomal degradation

Kylene Kehn, Cynthia de la Fuente, Katharine Strouss, Reem Berro, Hua Jiang, John Brady, Renaud Mahieux, Anne Pumfery, Maria Elena Bottazzi and Fatah Kashanchi

Oncogene 24: 525-540; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208105

Long-term controlled immortalization of a primate hepatic progenitor cell line after Simian virus 40 T-Antigen gene transfer

Jean-Paul Delgado, Alexandre Parouchev, Jean-Etienne Allain, Gaëlle Pennarun, Laurent R Gauthier, Anne-Marie Dutrillaux, Bernard Dutrillaux, James Di Santo, Frédérique Capron, François D Boussin and Anne Weber

Oncogene 24: 541-551; advance online publication, December 20, 2004; doi:10.1038/sj.onc.1208089

Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-beta1 expression

Corinne A Boulanger, Kay-Uwe Wagner and Gilbert H Smith

Oncogene 24: 552-560; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208185

HOXB4 confers a constant rate of in vitro proliferation to transduced bone marrow cells

Carolin Schmittwolf, Matthias Porsch, Axel Greiner, Andris Avots and Albrecht M Müller

Oncogene 24: 561-572; advance online publication, December 27, 2004; doi:10.1038/sj.onc.1208202

Selectively frequent expression of CXCR5 enhances resistance to apoptosis in CD8+CD34+ T cells from patients with T-cell-lineage acute lymphocytic leukemia

Zhang Qiuping, Xiong Jie, Jin Youxin, Wu Qun, Ju Wei, Liu Chun, Wang Jin, Liu Yan, Hu Chunsong, Yang Mingzhen, Gao Qingping, Li Qun, Zhang Kejian, Sun Zhimin, Liu Junyan and Tan Jinquan

Oncogene 24: 573-584; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208184

Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis

Irina V Lebedeva, Zao-zhong Su, Devanand Sarkar, Rahul V Gopalkrishnan, Samuel Waxman, Adly Yacoub, Paul Dent and Paul B Fisher

Oncogene 24: 585-596; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208183

beta-Catenin activates the growth factor endothelin-1 in colon cancer cells

Tae Hoon Kim, Hui Xiong, Zhuohua Zhang and Bing Ren

Oncogene 24: 597-604; advance online publication, November 22, 2004; doi:10.1038/sj.onc.1208237

Interferons alpha and bold italic gamma induce p53-dependent and p53-independent apoptosis, respectively

Chiara Porta, Reda Hadj-Slimane, Mohamed Nejmeddine, Mathieu Pampin, Michael G Tovey, Lucile Espert, Sandra Alvarez and Mounira K Chelbi-Alix

Oncogene 24: 605-615; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208204

Combined treatment with EGFR inhibitors and arsenite upregulated apoptosis in human EGFR-positive melanomas: a role of suppression of the PI3K-AKT pathway

Vladimir N Ivanov and Tom K Hei

Oncogene 24: 616-626; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208125

Caspase-1 activator Ipaf is a p53-inducible gene involved in apoptosis

Subhashini Sadasivam, Sanjeev Gupta, Vegesna Radha, Kiran Batta, Tapas K Kundu and Ghanshyam Swarup

Oncogene 24: 627-636; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208201

KAI1 promoter activity is dependent on p53, junB and AP2: evidence for a possible mechanism underlying loss of KAI1 expression in cancer cells

Alexandra Marreiros, Kip Dudgeon, Vinh Dao, Marc-Oliver Grimm, Robert Czolij, Merlin Crossley and Paul Jackson

Oncogene 24: 637-649; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208216

Ets1 is an effector of protein kinase Calpha in cancer cells

Martina Vetter, Sibylle G Blumenthal, Ralph K Lindemann, Joachim Manns, Sebastian Wesselborg, Christoph Thomssen and Jürgen Dittmer

Oncogene 24: 650-661; advance online publication, November 8, 2004; doi:10.1038/sj.onc.1208234

Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta

Amarsanaa Jazag, Hideaki Ijichi, Fumihiko Kanai, Takaaki Imamura, Bayasi Guleng, Miki Ohta, Jun Imamura, Yasuo Tanaka, Keisuke Tateishi, Tsuneo Ikenoue, Takayuki Kawakami, Yoshihiro Arakawa, Makoto Miyagishi, Kazunari Taira, Takao Kawabe and Masao Omata

Oncogene 24: 662-671; advance online publication, December 13, 2004; doi:10.1038/sj.onc.1208102

Alternative phospholipase D/mTOR survival signal in human breast cancer cells

Yuhong Chen, Vanessa Rodrik and David A Foster

Oncogene 24: 672-679; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208099

High activin A-expression in human neuroblastoma: suppression of malignant potential and correlation with favourable clinical outcome

Alexander Schramm, Volker von Schuetz, Holger Christiansen, Werner Havers, Maria Papoutsi, Jörg Wilting and Lothar Schweigerer

Oncogene 24: 680-687; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208087

Role of FLASH in caspase-8-mediated activation of NF-kappaB: dominant-negative function of FLASH mutant in NF-kappaB signaling pathway

Joon-Il Jun, Chul-Woong Chung, Ho-June Lee, Jong-Ok Pyo, Kee Nyung Lee, Nam-Soon Kim, Yong Sung Kim, Hyang-Sook Yoo, Tae-Ho Lee, Eunhee Kim and Yong-Keun Jung

Oncogene 24: 688-696; advance online publication, December 13, 2004; doi:10.1038/sj.onc.1208186

Tumor suppressive role of a 2.4 Mb 9q33−q34 critical region and DEC1 in esophageal squamous cell carcinoma

Lichun Yang, Alfred C C Leung, Josephine M Y Ko, Paulisally H Y Lo, Johnny C O Tang, Gopesh Srivastava, Mitsuo Oshimura, Eric J Stanbridge, Yataro Daigo, Yusuke Nakamura, Cecilia M C Tang, Kwok W Lau, Simon Law and Maria L Lung

Oncogene 24: 697-705; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208179

Restoring mismatch repair does not stop the formation of reciprocal translocations in the colon cancer cell line HCA7 but further destabilizes chromosome number

Wael M Abdel-Rahman, Hannes Lohi, Sakari Knuutila and Päivi Peltomäki

Oncogene 24: 706-713; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208129

17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo

Nan-Shan Chang, Lori Schultz, Li-Jin Hsu, Jennifer Lewis, Meng Su and Chun-I Sze

Oncogene 24: 714-723; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208124

Colon cancer secreted protein-2 (CCSP-2), a novel candidate serological marker of colon neoplasia

Baozhong Xin, Petra Platzer, Stephen P Fink, Lisa Reese, Arman Nosrati, James K V Willson, Keith Wilson and Sanford Markowitz

Oncogene 24: 724-731; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208134

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Oncogenomics

Differential methylation of genes that regulate cytokine signaling in lymphoid and hematopoietic tumors

Jyotsna Reddy, Narayan Shivapurkar, Takao Takahashi, Gunjan Parikh, Victor Stastny, Chinyere Echebiri, Katherine Crumrine, Sabine Zöchbauer-Müller, Johannes Drach, Yingye Zheng, Ziding Feng, Steven H Kroft, Robert W McKenna and Adi F Gazdar

Oncogene 24: 732-736; advance online publication, December 6, 2004; doi:10.1038/sj.onc.1208032

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