FIGURE 2
FROM:
Integration of high-resolution array comparative genomic hybridization analysis of chromosome 16q with expression array data refines common regions of loss at 16q23–qter and identifies underlying candidate tumor suppressor genes in prostate cancer
J E Vivienne Watson, Norman A Doggett, Donna G Albertson, Armann Andaya, Arul Chinnaiyan, Herman van Dekken, David Ginzinger, Christopher Haqq, Karen James, Sherwin Kamkar, David Kowbel, Daniel Pinkel, Lars Schmitt, Jeffry P Simko, Stanislav Volik, Vivian K Weinberg, Pamela L Paris and Colin Collins
BACK TO ARTICLEFigure 2.
Frequency of gains and losses on chromosome 16q. Array elements (BAC, PAC or cosmid clones) are placed along the x-axis according to the map position of the start of the clone (Ensembl Sept 2002 freeze, UCSC June 2002 freeze). The number of times a particular clone showed a significant copy number change in 16 CGH experiments is represented as a fraction and plotted either above the x-axis for gains (gray squares) or below the x-axis for losses (black triangles). Regions of loss in five or more tumors lie beneath the dashed line and are indicated by brackets. Those chosen for analysis and the candidate genes they contain are as follows: A WWOX; B MAF; C PLGC2; D CDH13; E WFDC1; F Q9H0B8; G NOC4; H ICSBP1; I FOXF1; J MVD; K FANCA. The arrow indicates approximate position of the common fragile site FRA16D
