FIGURE 1
FROM:
Integration of high-resolution array comparative genomic hybridization analysis of chromosome 16q with expression array data refines common regions of loss at 16q23–qter and identifies underlying candidate tumor suppressor genes in prostate cancer
J E Vivienne Watson, Norman A Doggett, Donna G Albertson, Armann Andaya, Arul Chinnaiyan, Herman van Dekken, David Ginzinger, Christopher Haqq, Karen James, Sherwin Kamkar, David Kowbel, Daniel Pinkel, Lars Schmitt, Jeffry P Simko, Stanislav Volik, Vivian K Weinberg, Pamela L Paris and Colin Collins
BACK TO ARTICLEFigure 1.
Chromosome 16q array CGH. Examples of 16q contig array CGH data. The map position of each genomic clone is represented along the x-axis. A value for the log 2 ratio of cy3/cy5 intensity for test/reference DNA is given for each clone. (a) Relative signal intensities for the average of four normal XY/XX hybridizations. Regions indicated 1–4 were selected as representatives of good hybridization (1 and 2), or poor hybridization (3 and 4), for sequence analysis by Genome Cryptographer. The region indicated by the bracket had a paucity of clones in the original contig. (b) Data for colon cancer cell line HCT116. (c) An example of CGH data for a single high-grade tumor (black). Data from the same tumor analysed on a 2400-element whole genome array are also shown for comparison (red)
