Oncogene

FIGURE 2

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Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis

Yi Wang, Sze Hang Lau, Jonathan Shun-Tong Sham, Meng-Chao Wu, Tao Wang and Xin-Yuan Guan

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Figure 2.

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Examples of rearrangements of X gene in HCC caused by HBV integration. X gene in four pairs of tumors (T) and their matched nontumor counterparts (N) were PCR amplified and the expected product is 664 bp. Normal size PCR product is observed in all nontumor samples and HCC sample in H37. PCR product is absent in HCC sample in H31 and H51 because of the deletion of the X gene. In H59, a larger PCR product is detected in HCC sample caused by a 278 bp insertion

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