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9 November 2000, Volume 19, Number 47

Table of Contents

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Original Papers
IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects FREE
L Behrend, D M Milne, M Stöter, W Deppert, L E Campbell, D W Meek & U Knippschild
Abstract  |  Full text  |  PDF 5303
Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells FREE
Charanjit Sandhu, Jeffrey Donovan, Nandita Bhattacharya, Martha Stampfer, Peter Worland & Joyce Slingerland
Abstract  |  Full text  |  PDF 5314
A cancer modifier role for parathyroid hormone-related protein FREE
Giacomo Manenti, Bernard Peissel, Manuela Gariboldi, F Stefania Falvella, Daniela Zaffaroni, Biagino Allaria, Simonetta Pazzaglia, Simonetta Rebessi, Vincenzo Covelli, Anna Saran & Tommaso A Dragani
Abstract  |  Full text  |  PDF 5324
Reduced latency but no increased brain tumor penetrance in mice with astrocyte specific expression of a human p53 mutant FREE
Michael A Klein, Daniela Rüedi, Michimasa Nozaki, Elizabeth W Dell, Annie-Claire Diserens, Walter Seelentag, Robert C Janzer, Adriano Aguzzi & Monika E Hegi
Abstract  |  Full text  |  PDF 5329
Loss of p21WAF1/CIP1 accelerates Ras oncogenesis in a transgenic/knockout mammary cancer model FREE
Jalila Adnane, Rosalind J Jackson, Santo V Nicosia, Alan B Cantor, W Jack Pledger & Saïd M Sebti
Abstract  |  Full text  |  PDF 5338
Regulation of a multigenic invasion programme by the transcription factor, AP-1: re-expression of a down-regulated gene, TSC-36, inhibits invasion FREE
Imogen MP Johnston, Heather J Spence, Joseph N Winnie, Lynn McGarry, J Keith Vass, Liam Meagher, Genevieve Stapleton & Bradford W Ozanne
Abstract  |  Full text  |  PDF 5348
Adenovirus-mediated p16INK4a gene expression radiosensitizes non-small cell lung cancer cells in a p53-dependent manner FREE
Shinichiro Kawabe, Jack A Roth, Deborah R Wilson & Raymond E Meyn
Abstract  |  Full text  |  PDF 5359
Oncogenic insertional mutations in the P-loop of Ras are overactive in MAP kinase signaling FREE
Boris Klockow, Mohammad R Ahmadian, Christoph Block & Alfred Wittinghofer
Abstract  |  Full text  |  PDF 5367
Synchronous and regulated expression of two AU-binding proteins, AUF1 and HuR, throughout murine development FREE
Agnès Gouble & Dominique Morello
Abstract  |  Full text  |  PDF 5377
Differential requirements of the MAP kinase and PI3 kinase signaling pathways in Src- versus insulin and IGF-1 receptors-induced growth and transformation of rat intestinal epithelial cells FREE
Kevin Tri Nguyen, Wang-June Wang, Joseph L-K Chan & Lu-Hai Wang
Abstract  |  Full text  |  PDF 5385
Chimeric VEGFRs are activated by a small-molecule dimerizer and mediate downstream signalling cascades in endothelial cells FREE
Emma L Knight, Andrea J Warner, Anthony Maxwell & Sally A Prigent
Abstract  |  Full text  |  PDF 5398
MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells FREE
Motoyoshi Tanaka, Dimpy Koul, Michael A Davies, Monica Liebert, Peter A Steck & H Barton Grossman
Abstract  |  Full text  |  PDF 5406
Short Report
Loss of heterozygosity, allele silencing and decreased expression of p73 gene in breast cancers: Prevalence of alterations in inflammatory breast cancers FREE
J C Ahomadegbe, S Tourpin, M Kaghad, L Zelek, M Vayssade, M C Mathieu, F Rochard, M Spielmann, T Tursz, D Caput, G Riou & J Bénard
Abstract  |  Full text  |  PDF 5413
9 November 2000, Volume 19, Number 47
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