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25 November 1999, Volume 18, Number 50

Table of Contents

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Articles
Association of hepatitis B virus X protein with mitochondria causes mitochondrial aggregation at the nuclear periphery, leading to cell death FREE
Shinako Takada, Yumiko Shirakata, Noriko Kaneniwa & Katsuro Koike
Abstract  |  Full text  |  PDF 6965
Role of c-Jun N-terminal kinase 1 (JNK1) in cell cycle checkpoint activated by the protease inhibitor N-acetyl-leucinyl-leucinyl-norleucinal FREE
Wen-Wei Tchou, Ting-An Yie, Tse-Hua Tan, William N Rom & Kam-Meng Tchou-Wong
Abstract  |  Full text  |  PDF 6974
MKP5, a new member of the MAP kinase phosphatase family, which selectively dephosphorylates stress-activated kinases FREE
Aspasia Theodosiou, Anna Smith, Corinne Gillieron, Steve Arkinstall & Alan Ashworth
Abstract  |  Full text  |  PDF 6981
Dual G1 and G2/M phase inhibition by SC-alphaalphadelta9, a combinatorially derived Cdc25 phosphatase inhibitor FREE
Kenji Tamura, Robert L Rice, Peter Wipf & John S Lazo
Abstract  |  Full text  |  PDF 6989
Impaired nucleotide excision repair in UV-irradiated human oral keratinocytes immortalized with type 16 human papillomavirus genome FREE
Osvaldo Rey, Sora Lee & No-Hee Park
Abstract  |  Full text  |  PDF 6997
Disruption of ATM in p53-null cells causes multiple functional abnormalities in cellular response to ionizing radiation FREE
Noriaki Takao, Hideaki Kato, Ryoichi Mori, Ciaran Morrison, Eiichiro Sonada, Xiango Sun, Hiroko Shimizu, Katsuji Yoshioka, Shunichi Takeda & Ken-ichi Yamamoto
Abstract  |  Full text  |  PDF 7002
Overexpression of dominant negative PARP interferes with tumor formation of HeLa cells in nude mice: Evidence for increased tumor cell apoptosis in vivo FREE
Margrit-Airin Hans, Marcus Müller, Mirella Meyer-Ficca, Alexander Bürkle & Jan-Heiner Küpper
Abstract  |  Full text  |  PDF 7010
Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53 FREE
J A Vrana, R H Decker, C R Johnson, Z Wang, W D Jarvis, V M Richon, M Ehinger, P B Fisher & S Grant
Abstract  |  Full text  |  PDF 7016
A novel exon within the mdm2 gene modulates translation initiation in vitro and disrupts the p53-binding domain of mdm2 protein FREE
Nik Veldhoen, Su Metcalfe & Jo Milner
Abstract  |  Full text  |  PDF 7026
The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells FREE
Yiling Lu, Yue-Zhen Lin, Ruth LaPushin, Bruce Cuevas, Xianjun Fang, Shuang Xing Yu, Michael A Davies, Humera Khan, Tatsuro Furui, Muling Mao, Ralph Zinner, Mien-Chi Hung, Peter Steck, Kathy Siminovitch & Gordon B Mills
Abstract  |  Full text  |  PDF 7034
An FH domain-containing Bnr1p is a multifunctional protein interacting with a variety of cytoskeletal proteins in Saccharomyces cerevisiae FREE
Mitsuhiro Kikyo, Kazuma Tanaka, Takashi Kamei, Kumi Ozaki, Takeshi Fujiwara, Eiji Inoue, Yoko Takita, Yoshikazu Ohya & Yoshimi Takai
Abstract  |  Full text  |  PDF 7046
Characterization of the chronic myelomonocytic leukemia associated TEL-PDGFbold betaR fusion protein FREE
Tobias Sjöblom, Anthony Boureux, Lars Rönnstrand, Carl-Henrik Heldin, Jacques Ghysdael & Arne Östman
Abstract  |  Full text  |  PDF 7055
Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinoma FREE
Adel K El-Naggar, Syeling Lai, Susan A Tucker, Gary L Clayman, Helmuth Goepfert, Waun Ki Hong & Vicki Huff
Abstract  |  Full text  |  PDF 7063
Isolation and characterization of Xenopus ATM (X-ATM): expression, localization, and complex formation during oogenesis and early development FREE
Kirsten Robertson, Carmel Hensey & Jean Gautier
Abstract  |  Full text  |  PDF 7070
Calcium influx triggers the sequential proteolysis of extracellular and cytoplasmic domains of E-cadherin, leading to loss of bold beta-catenin from cell - cell contacts FREE
Kiyoharu Ito, Isamu Okamoto, Norie Araki, Yoshiaki Kawano, Mitsuyoshi Nakao, Shigetoshi Fujiyama, Kimio Tomita, Tatsuyuki Mimori & Hideyuki Saya
Abstract  |  Full text  |  PDF 7080
The promyelocytic leukemia protein PML interacts with the proline-rich homeodomain protein PRH: a RING may link hematopoiesis and growth control FREE
Zeki Topcu, David L Mack, Robert A Hromas & Katherine LB Borden
Abstract  |  Full text  |  PDF 7091
SIAH-1 inhibits cell growth by altering the mitotic process FREE
H Bruzzoni-Giovanelli, A Faille, G Linares-Cruz, M Nemani, F Le Deist, A Germani, D Chassoux, G Millot, J-P Roperch, R Amson, A Telerman & F Calvo
Abstract  |  Full text  |  PDF 7101
bold gamma-Heregulin: a fusion gene of DOC-4 and neuregulin-1 derived from a chromosome translocation FREE
Xifu Liu, Elizabeth Baker, Helen J Eyre, Grant R Sutherland & Mingdong Zhou
Abstract  |  Full text  |  PDF 7110
Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation FREE
Shirley Guofang Qiu, Sumathi Krishnan, Nadia El-Guendy & Vivek M Rangnekar
Abstract  |  Full text  |  PDF 7115
A full-length Cbfa1 gene product perturbs T-cell development and promotes lymphomagenesis in synergy with MYC FREE
François Vaillant, Karen Blyth, Anne Terry, Margaret Bell, Ewan R Cameron, James Neil & Monica Stewart
Abstract  |  Full text  |  PDF 7124
SHIP-mediated inhibition of K562 erythroid differentiation requires an intact catalytic domain and Shc binding site FREE
Josie Siegel, Yun Li & Peter Whyte
Abstract  |  Full text  |  PDF 7135
Ras stimulates DNA topoisomerase IIalpha through MEK: A link between oncogenic signaling and a therapeutic target FREE
Guan Chen, Dennis Templeton, D Parker Suttle & Dennis W Stacey
Abstract  |  Full text  |  PDF 7149
Short report
Latent membrane protein 1 associated signaling pathways are important in tumor cells of Epstein-Barr virus negative Hodgkin's disease FREE
Hans Knecht, Christoph Berger, Cathy McQuain, Sylvia Rothenberger, Edith Bachmann, Jennifer Martin, Christoph Esslinger, Hans G Drexler, Yun C Cai, Peter J Quesenberry & Bernhard F Odermatt
Abstract  |  Full text  |  PDF 7161
Inhibition of growth of human malignant glioblastoma in nude mice by antagonists of bombesin/gastrin-releasing peptide FREE
H Kiaris, A V Schally, B Sun, P Armatis & K Groot
Abstract  |  Full text  |  PDF 7168
Murine Siva-1 and Siva-2, alternate splice forms of the mouse Siva gene, both bind to CD27 but differentially transduce apoptosis FREE
Yoosik Yoon, Zhaohui Ao, Yuan Cheng, Stuart F Schlossman & K V S Prasad
Abstract  |  Full text  |  PDF 7174
Search for in vivo somatic mutations in the mitotic checkpoint gene, hMAD1, in human lung cancers FREE
Shuji Nomoto, Nobuhiro Haruki, Takao Takahashi, Akira Masuda, Takashi Koshikawa, Toshitada Takahashi, Yoshitaka Fujii, Hirotaka Osada & Takashi Takahashi
Abstract  |  Full text  |  PDF 7180
25 November 1999, Volume 18, Number 50
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