Subjects - Genome sequence and analysis

  • Animals

    • Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting

      Nature Chemical Biology
      17 May 2009

  • Archaea

    • Fifteen years of microbial genomics: meeting the challenges and fulfilling the dream

      Nature Biotechnology
      8 July 2009

  • Arthropods

    • ChIP–seq: advantages and challenges of a maturing technology

      Nature Reviews Genetics
      8 September 2009

    • The genetics of quantitative traits: challenges and prospects

      Nature Reviews Genetics
      1 August 2009

  • Bacteria

    • Computational methods for discovering structural variation with next-generation sequencing

      Nature Methods
      15 October 2009

    • Network coverage

      PSI Structural Genomics Knowledgebase
      14 October 2009

    • Technology: The sequencing game

      Nature Reviews Genetics
      1 August 2009

    • Unravelling ancient microbial history with community proteogenomics and lipid geochemistry

      Nature Reviews Microbiology
      1 August 2009

    • The versatility and adaptation of bacteria from the genus Stenotrophomonas

      Nature Reviews Microbiology
      1 July 2009

    • Small RNAs: Microbial metatranscriptomics goes deep

      Nature Reviews Genetics
      9 June 2009

    • Application of 'next-generation' sequencing technologies to microbial genetics

      Nature Reviews Microbiology
      23 February 2009

    • Host genetics: Opening the door to TB

      Nature Reviews Microbiology
      1 February 2009

  • Eukaryotes

    • Computational methods for discovering structural variation with next-generation sequencing

      Nature Methods
      15 October 2009

    • Sense from sequence reads: methods for alignment and assembly

      Nature Methods
      15 October 2009

    • The genetics of quantitative traits: challenges and prospects

      Nature Reviews Genetics
      1 August 2009

  • Firmicutes

    • Fifteen years of microbial genomics: meeting the challenges and fulfilling the dream

      Nature Biotechnology
      8 July 2009

  • Fungi

    • Small RNAs: Budding new models for RNAi

      Nature Reviews Genetics
      22 September 2009

    • From DNA sequence to transcriptional behaviour: a quantitative approach

      Nature Reviews Genetics
      1 July 2009

    • Genome sequence of the recombinant protein production host Pichia pastoris

      Nature Biotechnology
      24 May 2009

    • Prions: Prying into prions

      Nature Reviews Microbiology
      29 April 2009

    • Population genetics: A portrait of yeast

      Nature Reviews Genetics
      1 April 2009

  • Green plants

    • The genetics of quantitative traits: challenges and prospects

      Nature Reviews Genetics
      1 August 2009

  • Human

    • Common disorders are quantitative traits

      Nature Reviews Genetics
      27 October 2009

    • A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

      Nature Genetics
      18 October 2009

    • Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

      Nature Genetics
      18 October 2009

    • Human genomics: Structural variation catches up

      Nature Reviews Genetics
      13 October 2009

    • Pharmacogenetics: A SNP for hepatitis C treatment failure

      Nature Reviews Genetics
      13 October 2009

    • Common variants in TMPRSS6 are associated with iron status and erythrocyte volume

      Nature Genetics
      11 October 2009

    • Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels

      Nature Genetics
      11 October 2009

    • Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

      Nature Genetics
      11 October 2009

    • A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

      Nature Genetics
      11 October 2009

    • Finding the missing heritability of complex diseases

      Nature
      8 October 2009

    • Human genetics: Hit or miss?

      Nature
      7 October 2009

    • An agenda for personalized medicine

      Nature
      7 October 2009

    • Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

      Nature Genetics
      4 October 2009

    • A new statistic and its power to infer membership in a genome-wide association study using genotype frequencies

      Nature Genetics
      4 October 2009

    • Bayesian statistical methods for genetic association studies

      Nature Reviews Genetics
      1 October 2009

    • Identification of a new prostate cancer susceptibility locus on chromosome 8q24

      Nature Genetics
      20 September 2009

    • Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

      Nature Genetics
      20 September 2009

    • Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

      Nature Genetics
      20 September 2009

    • Multiple loci on 8q24 associated with prostate cancer susceptibility

      Nature Genetics
      20 September 2009

    • Technology: A step closer to personal genomics?

      Nature Reviews Genetics
      15 September 2009

    • IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

      Nature Genetics
      13 September 2009

    • Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

      Nature Genetics
      13 September 2009

    • Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

      Nature Genetics
      6 September 2009

    • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

      Nature Genetics
      6 September 2009

    • Personalized copy number and segmental duplication maps using next-generation sequencing

      Nature Genetics
      30 August 2009

    • Single-molecule sequencing of an individual human genome

      Nature Biotechnology
      10 August 2009

    • The genetics of quantitative traits: challenges and prospects

      Nature Reviews Genetics
      1 August 2009

    • Complex disease: Schizophrenia: missing heritability found?

      Nature Reviews Genetics
      1 August 2009

    • Technology: The sequencing game

      Nature Reviews Genetics
      1 August 2009

    • Neurogenetics: Schizophrenia: missing heritability found?

      Nature Reviews Neuroscience
      1 August 2009

    • A highly annotated whole-genome sequence of a Korean individual

      Nature
      8 July 2009

    • From DNA sequence to transcriptional behaviour: a quantitative approach

      Nature Reviews Genetics
      1 July 2009

    • The genetic contribution to non-syndromic human obesity

      Nature Reviews Genetics
      1 July 2009

    • An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors

      Oncogene
      15 June 2009

    • Combined genomic and gene expression microarray profiling identifies ECOP as an upregulated gene in squamous cell carcinomas independent of DNA amplification

      Oncogene
      15 June 2009

    • New insights into the aetiology of colorectal cancer from genome-wide association studies

      Nature Reviews Genetics
      1 June 2009

    • Detecting gene–gene interactions that underlie human diseases

      Nature Reviews Genetics
      1 June 2009

    • Complex disease: Autism clues from genome-wide studies

      Nature Reviews Genetics
      1 June 2009

    • Neurogenetics: Common changes in autism

      Nature Reviews Neuroscience
      1 June 2009

    • Evaluation of C1q genomic region in minority racial groups of lupus

      Genes and Immunity
      14 May 2009

    • Validating, augmenting and refining genome-wide association signals

      Nature Reviews Genetics
      1 May 2009

    • Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies

      Nature Reviews Genetics
      1 May 2009

    • Functional genomics: Structure provides clues

      Nature Reviews Genetics
      1 May 2009

    • Genetics of gene expression: Putting radiation response on the map

      Nature Reviews Genetics
      1 May 2009

    • Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

      Nature
      28 April 2009

    • Developmental programming of CpG island methylation profiles in the human genome

      Nature Structural & Molecular Biology
      19 April 2009

    • Beyond odds ratios — communicating disease risk based on genetic profiles

      Nature Reviews Genetics
      1 April 2009

    • New insights into the genetics of addiction

      Nature Reviews Genetics
      1 April 2009

    • Human genetic variation and its contribution to complex traits

      Nature Reviews Genetics
      1 April 2009

    • Personal genomics services: whose genomes?

      European Journal of Human Genetics
      4 March 2009

    • Integrative genomics, personal-genome tests and personalized healthcare: the future is being built today

      European Journal of Human Genetics
      4 March 2009

    • Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

      Nature Biotechnology
      1 February 2009

    • p53 polymorphisms: cancer implications

      Nature Reviews Cancer
      1 February 2009

    • Alternative splicing: Deciding between the alternatives

      Nature Reviews Genetics
      1 February 2009

    • Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype

      Nature Reviews Cancer
      16 January 2009

    • Direct-to-consumer genome scanning services. Also for children?

      Nature Reviews Genetics
      1 January 2009

    • Human disease: Genome-wide insights into lipid levels

      Nature Reviews Genetics
      1 January 2009

  • Mammals

    • ChIP–seq: advantages and challenges of a maturing technology

      Nature Reviews Genetics
      8 September 2009

    • Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

      Nature Immunology
      13 July 2009

    • Mapping genes for complex traits in domestic animals and their use in breeding programmes

      Nature Reviews Genetics
      1 June 2009

    • Genomics: Milking the cow genome

      Nature Reviews Genetics
      1 June 2009

  • Nematodes

  • Proteobacteria

    • Fifteen years of microbial genomics: meeting the challenges and fulfilling the dream

      Nature Biotechnology
      8 July 2009

  • Rodents

    • The genetics of quantitative traits: challenges and prospects

      Nature Reviews Genetics
      1 August 2009

    • Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

      Nature Immunology
      13 July 2009

    • Mina, an Il4 repressor, controls T helper type 2 bias

      Nature Immunology
      28 June 2009

    • Gene expression: Complex interactions

      Nature Reviews Molecular Cell Biology
      10 June 2009

    • Towards better mouse models: enhanced genotypes, systemic phenotyping and envirotype modelling

      Nature Reviews Genetics
      1 June 2009

  • Viruses

    • Pharmacogenetics: A SNP for hepatitis C treatment failure

      Nature Reviews Genetics
      13 October 2009

    • IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

      Nature Genetics
      13 September 2009

    • Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

      Nature Genetics
      13 September 2009

    • Application of 'next-generation' sequencing technologies to microbial genetics

      Nature Reviews Microbiology
      23 February 2009

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