Subjects - Cancer genomics

  • Human

    • Epigenetic stem cell signature in cancer

      Nature Genetics
      31 December 2006
    • Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

      Nature Genetics
      31 December 2006
    • Targeting Interferon-alpha Increases Antitumor Efficacy and Reduces Hepatotoxicity of E1A-mutated Spread-enhanced Oncolytic Adenovirus

      Molecular Therapy
      26 December 2006
    • Breast-specific expression of MGB1/mammaglobin: an examination of 480 tumors from various organs and clinicopathological analysis of MGB1-positive breast cancers

      Modern Pathology
      22 December 2006
    • Integrative molecular concept modeling of prostate cancer progression

      Nature Genetics
      17 December 2006
    • Computational prediction of cancer-gene function

      Nature Reviews Cancer
      14 December 2006
    • Cancer phenomics: RET and PTEN as illustrative models

      Nature Reviews Cancer
      14 December 2006
    • Distinct Clinical and Pathological Features Are Associated with the BRAFT1799A(V600E) Mutation in Primary Melanoma

      Journal of Investigative Dermatology
      7 December 2006
    • Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy

      British Journal of Cancer
      28 November 2006
    • Frequent homogeneous HER-2 amplification in primary and metastatic adenocarcinoma of the esophagus

      Modern Pathology
      24 November 2006
    • HDM4 (HDMX) is widely expressed in adult pre-B acute lymphoblastic leukemia and is a potential therapeutic target

      Modern Pathology
      24 November 2006
    • Expression profiles associated with aggressive behavior in Merkel cell carcinoma

      Modern Pathology
      17 November 2006
    • TIM-3 Is Expressed in Melanoma Cells and Is Upregulated in TGF-Beta Stimulated Mast Cells

      Journal of Investigative Dermatology
      9 November 2006
    • Loss of nuclear p27 (CDKN1B/KIP1) in colorectal cancer is correlated with microsatellite instability and CIMP

      Modern Pathology
      3 November 2006
    • Gene expression response to cisplatin treatment in drug-sensitive and drug-resistant ovarian cancer cells

      Oncogene
      30 October 2006
    • A genome-wide scan for naevus count: linkage to CDKN2A and to other chromosome regions

      European Journal of Human Genetics
      25 October 2006
    • Sequence analysis proves clonal identity in five patients with typical and blastoid mantle cell lymphoma

      Modern Pathology
      20 October 2006
    • Role of hypoxia inducible factor-1 alpha in modulation of apoptosis resistance

      Oncogene
      16 October 2006
    • Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia

      Oncogene
      16 October 2006
    • Regulation of clustered gene expression by cofactor of BRCA1 (COBRA1) in breast cancer cells

      Oncogene
      16 October 2006
    • Genetic variance modifies apoptosis susceptibility in mature oocytes via alterations in DNA repair capacity and mitochondrial ultrastructure

      Cell Death and Differentiation
      13 October 2006
    • Molecular pathways in follicular lymphoma

      Leukemia
      12 October 2006
    • The Mitochondrial DNA Common Deletion Is Present in Most Basal and Squamous Cell Carcinoma Samples Isolated by Laser Capture Microdissection but Generally at Reduced Rather than Increased Levels

      Journal of Investigative Dermatology
      12 October 2006
    • Snail silencing effectively suppresses tumour growth and invasiveness

      Oncogene
      9 October 2006
    • E2F4 regulates a stable G2 arrest response to genotoxic stress in prostate carcinoma

      Oncogene
      9 October 2006
    • Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the bold beta4 integrin and the PI3k pathway

      Oncogene
      9 October 2006
    • Ionizing radiation activates IGF-1R triggering a cytoprotective signaling by interfering with Ku-DNA binding and by modulating Ku86 expression via a p38 kinase-dependent mechanism

      Oncogene
      9 October 2006
    • Prognosis of stage II colon cancer by non-neoplastic mucosa gene expression profiling

      Oncogene
      9 October 2006
    • Genistein inhibits Brca1 mutant tumor growth through activation of DNA damage checkpoints, cell cycle arrest, and mitotic catastrophe

      Cell Death and Differentiation
      6 October 2006
    • XLX is an IAP family member regulated by phosphorylation during meiosis

      Cell Death and Differentiation
      29 September 2006
    • The single-nucleotide polymorphism 309 in the MDM2 gene contributes to the Li–Fraumeni syndrome and related phenotypes

      European Journal of Human Genetics
      27 September 2006
    • Androgen induces expression of the multidrug resistance protein gene MRP4 in prostate cancer cells

      Prostate Cancer and Prostatic Diseases
      26 September 2006
    • Autophagy delays apoptotic death in breast cancer cells following DNA damage

      Cell Death and Differentiation
      22 September 2006
    • Genetic Variants of the Vitamin D Receptor Gene Alter Risk of Cutaneous Melanoma

      Journal of Investigative Dermatology
      21 September 2006
    • Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway

      Oncogene
      18 September 2006
    • Genetic induction of tumorigenesis in Swine

      Oncogene
      11 September 2006
    • Characterizing a rat Brca2 knockout model

      Oncogene
      11 September 2006
    • Transcriptional regulation of KiSS-1 gene expression in metastatic melanoma by specificity protein-1 and its coactivator DRIP-130

      Oncogene
      11 September 2006
    • WS5, a direct target of oncogenic transcription factor Myc, is related to human melanoma glycoprotein genes and has oncogenic potential

      Oncogene
      11 September 2006
    • KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression

      Oncogene
      4 September 2006
    • DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells

      Cell Death and Differentiation
      1 September 2006
    • Abl deregulates Cdk5 kinase activity and subcellular localization in Drosophila neurodegeneration

      Cell Death and Differentiation
      25 August 2006
    • The role of 5' untranslated region in translational suppression of OKL38 mRNA in hepatocellular carcinoma

      Oncogene
      21 August 2006
    • Raf 1 represses expression of the tight junction protein occludin via activation of the zinc-finger transcription factor slug

      Oncogene
      21 August 2006
    • Cigarette smoke condensate-induced level of adenomatous polyposis coli blocks long-patch base excision repair in breast epithelial cells

      Oncogene
      21 August 2006
    • Hypoxia induces p53-dependent transactivation and Fas/CD95-dependent apoptosis

      Cell Death and Differentiation
      18 August 2006
    • Transfer of chromosome 3 fragments suppresses tumorigenicity of an ovarian cancer cell line monoallelic for chromosome 3p

      Oncogene
      7 August 2006
    • Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor

      Oncogene
      7 August 2006
    • RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer

      Oncogene
      31 July 2006
    • A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas

      Oncogene
      31 July 2006
    • Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers

      Oncogene
      31 July 2006
    • NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2

      Oncogene
      24 July 2006
    • Neurotensin stimulates mitogenesis of prostate cancer cells through a novel c-Src/Stat5b pathway

      Oncogene
      24 July 2006
  • Rodents

    • Targeting Interferon-alpha Increases Antitumor Efficacy and Reduces Hepatotoxicity of E1A-mutated Spread-enhanced Oncolytic Adenovirus

      Molecular Therapy
      26 December 2006
    • Computational prediction of cancer-gene function

      Nature Reviews Cancer
      14 December 2006
    • Cancer phenomics: RET and PTEN as illustrative models

      Nature Reviews Cancer
      14 December 2006
    • Cyclooxygenase-2 Inhibition Promotes Enhancement of Antitumor Responses by Transcutaneous Vaccination with Cytosine-Phosphate-Guanosine-Oligodeoxynucleotides and Model Tumor Antigen

      Journal of Investigative Dermatology
      7 December 2006
    • Protective Effect of Hyperpigmented Skin on UV-Mediated Cutaneous Cancer Development

      Journal of Investigative Dermatology
      7 December 2006
    • Cyclin D2 and cyclin D3 play opposite roles in mouse skin carcinogenesis

      Oncogene
      18 September 2006

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