Organisms - Human

  • Cancer genomics

    • Tissue microarray analyses of G1/S-regulatory proteins in ductal carcinoma in situ of the breast indicate that low cyclin D1 is associated with local recurrence

      British Journal of Cancer
      17 November 2003

    • Diagnostic and prognostic prediction using gene expression profiles in high-dimensional microarray data

      British Journal of Cancer
      3 November 2003

    • Clinical implications of radiation-induced genomic instability

      Oncogene
      13 October 2003

    • Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation

      Oncogene
      13 October 2003

    • DNA microarray analysis of hematopoietic stem cell-like fractions from individuals with the M2 subtype of acute myeloid leukemia

      Leukemia
      1 October 2003

    • Radiation-induced genomic instability and its implications for radiation carcinogenesis

      Oncogene
      1 September 2003

    • Comparing Fluorescence In Situ Hybridization and Chromogenic In Situ Hybridization Methods to Determine the HER2/neu Status in Primary Breast Carcinoma using Tissue Microarray

      Modern Pathology
      1 September 2003

    • Prognostic value of genomic alterations in head and neck squamous cell carcinoma detected by comparative genomic hybridisation

      British Journal of Cancer
      1 September 2003

    • Proteomic analysis of hematopoietic stem cell-like fractions in leukemic disorders

      Oncogene
      28 August 2003

    • Proteomic analysis of the cell-surface membrane in chronic lymphocytic leukemia: identification of two novel proteins, BCNP1 and MIG2B

      Leukemia
      1 August 2003

    • Chromosome aberrations in solid tumors

      Nature Genetics
      30 July 2003

    • Proteome analysis enables separate clustering of normal breast, benign breast and breast cancer tissues

      British Journal of Cancer
      21 July 2003

    • Genome-wide-array-based comparative genomic hybridization reveals genetic homogeneity and frequent copy number increases encompassing CCNE1 in Fallopian tube carcinoma

      Oncogene
      3 July 2003

    • DNA microarrays for comparison of gene expression profiles between diagnosis and relapse in precursor-B acute lymphoblastic leukemia: choice of technique and purification influence the identification of potential diagnostic markers

      Leukemia
      1 July 2003

    • BARCODE-ALL: accelerated and cost-effective genetic risk stratification in acute leukemia using spectrally addressable liquid bead microarrays

      Leukemia
      1 July 2003

    • BARCODE-ALL: accelerated and cost-effective genetic risk stratification in acute leukemia using spectrally addressable liquid bead microarrays

      Leukemia
      1 July 2003

    • Spatial proximity of translocation-prone gene loci in human lymphomas

      Nature Genetics
      15 June 2003

    • Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer

      Oncogene
      12 June 2003

    • Sequence-based cancer genomics: progress, lessons and opportunities

      Nature Reviews Genetics
      1 June 2003

    • Cytogenetic alterations in ovarian clear cell carcinoma detected by comparative genomic hybridisation

      British Journal of Cancer
      19 May 2003

    • Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer

      Oncogene
      15 May 2003

    • Genomic analysis of primary tumors does not address the prevalence of metastatic cells in the population

      Nature Genetics
      1 May 2003

    • Genetic background is an important determinant of metastatic potential

      Nature Genetics
      1 May 2003

    • Reply to "Genomic analysis of primary tumors does not address the prevalence of metastatic cells in the population" and "Genetic background is an important determinant of metastatic potential"

      Nature Genetics
      1 May 2003

    • Characteristic sequence motifs located at the genomic breakpoints of the translocation t(X;18) in synovial sarcomas

      Oncogene
      10 April 2003

    • DNA Arrays in Clinical Oncology: Promises and Challenges

      Laboratory Investigation
      1 March 2003

    • The genetics and genomics of cancer

      Nature Genetics
      1 March 2003

    • hTERT associates with human telomeres and enhances genomic stability and DNA repair

      Oncogene
      9 January 2003

  • Comparative, evolutionary and population genomics

    • The power and promise of population genomics: from genotyping to genome typing

      Nature Reviews Genetics
      1 December 2003

    • The DNA sequence and analysis of human chromosome 6

      Nature
      23 October 2003

    • Induced genomic instability in irradiated germ cells and in the offspring; reconciling discrepancies among the human and animal studies

      Oncogene
      13 October 2003

    • Evolution thinks modular

      Nature Genetics
      1 October 2003

    • It's a bullseye!

      Nature Reviews Genetics
      1 September 2003

    • Comparative analyses of multi-species sequences from targeted genomic regions

      Nature
      14 August 2003

    • Evolutionary and ecological functional genomics

      Nature Reviews Genetics
      1 August 2003

    • The DNA sequence of human chromosome 7

      Nature
      10 July 2003

    • Genome biology: Tales of the Y chromosome

      Nature
      19 June 2003

    • The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes

      Nature
      19 June 2003

    • Abundant gene conversion between arms of palindromes in human and ape Y chromosomes

      Nature
      19 June 2003

    • Genome evolution: Let's stick together

      Heredity
      1 June 2003

    • Alternative splicing in the human, mouse and rat genomes is associated with an increased frequency of exon creation and/or loss

      Nature Genetics
      5 May 2003

    • Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases

      Oncogene
      10 April 2003

    • Comparative genomics: genome-wide analysis in metazoan eukaryotes

      Nature Reviews Genetics
      1 April 2003

    • Transcription-associated mutational asymmetry in mammalian evolution

      Nature Genetics
      3 March 2003

    • The application of molecular genetic approaches to the study of human evolution

      Nature Genetics
      1 March 2003

    • Comparative Genomics: Genomes of mice and men

      Heredity
      1 February 2003

    • The DNA sequence and analysis of human chromosome 14

      Nature
      1 January 2003

  • Epigenomics

    • Induced genomic instability in irradiated germ cells and in the offspring; reconciling discrepancies among the human and animal studies

      Oncogene
      13 October 2003

    • Radiation-induced genomic instability and its implications for radiation carcinogenesis

      Oncogene
      1 September 2003

    • Epigenetic interplay

      Nature Genetics
      1 June 2003

    • Chromatin remodeling and extragenic transcription at the MHC class II locus control region

      Nature Immunology
      13 January 2003

  • Genetics of Gene Expression

    • Proteomic analysis of hematopoietic stem cell-like fractions in leukemic disorders

      Oncogene
      28 August 2003

    • Wanted: regulatory SNPs

      Nature Genetics
      1 April 2003

    • In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading

      Nature Genetics
      10 March 2003

    • Natural variation in human gene expression assessed in lymphoblastoid cells

      Nature Genetics
      3 February 2003

  • Genome sequence and analysis

    • Genome-wide TDT analysis in a localized population with a high prevalence of multiple sclerosis indicates the importance of a region on chromosome 14q

      Genes and Immunity
      1 December 2003

    • Genomics: Six is seventh

      Nature
      23 October 2003

    • The DNA sequence and analysis of human chromosome 6

      Nature
      23 October 2003

    • Genome-wide scanning for linkage in Finnish breast cancer families

      European Journal of Human Genetics
      15 October 2003

    • Parametric and nonparametric genome scan analyses for human handedness

      European Journal of Human Genetics
      1 October 2003

    • Teaching genomics: confusion and clarity

      Nature Genetics
      1 October 2003

    • Genomic empowerment: the importance of public databases

      Nature Genetics
      1 September 2003

    • A user's guide to the human genome

      Nature Genetics
      1 September 2003

    • Comparative analyses of multi-species sequences from targeted genomic regions

      Nature
      14 August 2003

    • Different Applications of Polymerases With and Without Proofreading Activity in Single-Nucleotide Polymorphism Analysis

      Laboratory Investigation
      1 August 2003

    • Haplotype blocks and linkage disequilibrium in the human genome

      Nature Reviews Genetics
      1 August 2003

    • The DNA sequence of human chromosome 7

      Nature
      10 July 2003

    • Genome-wide-array-based comparative genomic hybridization reveals genetic homogeneity and frequent copy number increases encompassing CCNE1 in Fallopian tube carcinoma

      Oncogene
      3 July 2003

    • A singular chromosome

      Nature Genetics
      1 July 2003

    • Genome biology: Tales of the Y chromosome

      Nature
      19 June 2003

    • The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes

      Nature
      19 June 2003

    • Abundant gene conversion between arms of palindromes in human and ape Y chromosomes

      Nature
      19 June 2003

    • Zinc-Based Fixative Improves Preservation of Genomic DNA and Proteins in Histoprocessing of Human Tissues

      Laboratory Investigation
      1 June 2003

    • HUGO—a UN for the human genome

      Nature Genetics
      1 June 2003

    • From the ground up

      Nature Genetics
      1 May 2003

    • Quality and completeness of SNP databases

      Nature Genetics
      24 March 2003

    • Widespread occurrence of antisense transcription in the human genome

      Nature Biotechnology
      17 March 2003

    • Combined analysis of genomewide scans for adult height: results from the NHLBI Family Blood Pressure Program

      European Journal of Human Genetics
      1 March 2003

    • Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

      Nature Genetics
      1 March 2003

    • The genome era begins...

      Nature Genetics
      1 March 2003

    • Massive parallelism, randomness and genomic advances

      Nature Genetics
      1 March 2003

    • Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays

      Oncogene
      27 February 2003

    • Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots

      Nature Genetics
      18 February 2003

    • Segments missing from the draft human genome sequence can be isolated by transformation-associated recombination cloning in yeast

      EMBO reports
      7 February 2003

    • Genome-wide search in Finnish families with inflammatory bowel disease provides evidence for novel susceptibility loci

      European Journal of Human Genetics
      1 February 2003

    • Comparative Genomics: Genomes of mice and men

      Heredity
      1 February 2003

    • Signatures of natural selection in the human genome

      Nature Reviews Genetics
      1 February 2003

    • The DNA sequence and analysis of human chromosome 14

      Nature
      1 January 2003

  • Metabolomics/nomics

  • Pharmacogenomics

    • Pharmacogenetics goes genomic

      Nature Reviews Genetics
      1 December 2003

    • Genomic profiling to promote a healthy lifestyle: not ready for prime time

      Nature Genetics
      1 August 2003

    • Reality check for pharmacogenomics

      Nature Genetics
      1 June 2003

    • Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells

      Nature Genetics
      21 April 2003

  • Proteomics

    • Gaining confidence in high-throughput protein interaction networks

      Nature Biotechnology
      14 December 2003

    • Comparing Fluorescence In Situ Hybridization and Chromogenic In Situ Hybridization Methods to Determine the HER2/neu Status in Primary Breast Carcinoma using Tissue Microarray

      Modern Pathology
      1 September 2003

    • Proteomic analysis of the cell-surface membrane in chronic lymphocytic leukemia: identification of two novel proteins, BCNP1 and MIG2B

      Leukemia
      1 August 2003

    • Proteome analysis enables separate clustering of normal breast, benign breast and breast cancer tissues

      British Journal of Cancer
      21 July 2003

    • Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry

      Nature Biotechnology
      18 May 2003

    • proteomics

      Nature
      13 March 2003

    • From genomics to proteomics

      Nature
      13 March 2003

    • Mass spectrometry-based proteomics

      Nature
      13 March 2003

    • Protein analysis on a proteomic scale

      Nature
      13 March 2003

    • From words to literature in structural proteomics

      Nature
      13 March 2003

    • Disease proteomics

      Nature
      13 March 2003

    • Biomedical informatics for proteomics

      Nature
      13 March 2003

    • The application of mass spectrometry to membrane proteomics

      Nature Biotechnology
      1 March 2003

    • Integration from proteins to organs: the Physiome Project

      Nature Reviews Molecular Cell Biology
      1 March 2003

    • Characterization of the human heart mitochondrial proteome

      Nature Biotechnology
      18 February 2003

    • A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling

      Nature Biotechnology
      10 February 2003

    • Is proteomics heading in the wrong direction?

      Nature Reviews Molecular Cell Biology
      1 January 2003

  • Systems biology

    • Gaining confidence in high-throughput protein interaction networks

      Nature Biotechnology
      14 December 2003

    • Evolution thinks modular

      Nature Genetics
      1 October 2003

    • Total interconnectedness of everything

      Nature Reviews Genetics
      1 October 2003

    • Systems biology and elephants

      Nature Cell Biology
      1 April 2003

    • Building a cell cycle oscillator: hysteresis and bistability in the activation of Cdc2

      Nature Cell Biology
      10 March 2003

  • Techniques and methods

    • Gaining confidence in high-throughput protein interaction networks

      Nature Biotechnology
      14 December 2003

    • Diagnostic and prognostic prediction using gene expression profiles in high-dimensional microarray data

      British Journal of Cancer
      3 November 2003

    • Prognostic value of genomic alterations in head and neck squamous cell carcinoma detected by comparative genomic hybridisation

      British Journal of Cancer
      1 September 2003

    • Proteome analysis enables separate clustering of normal breast, benign breast and breast cancer tissues

      British Journal of Cancer
      21 July 2003

    • BARCODE-ALL: accelerated and cost-effective genetic risk stratification in acute leukemia using spectrally addressable liquid bead microarrays

      Leukemia
      1 July 2003

    • BARCODE-ALL: accelerated and cost-effective genetic risk stratification in acute leukemia using spectrally addressable liquid bead microarrays

      Leukemia
      1 July 2003

    • Zinc-Based Fixative Improves Preservation of Genomic DNA and Proteins in Histoprocessing of Human Tissues

      Laboratory Investigation
      1 June 2003

    • Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry

      Nature Biotechnology
      18 May 2003

    • How to book for microarrays

      Nature Genetics
      1 May 2003

    • Integrating biological databases

      Nature Reviews Genetics
      1 May 2003

    • Microarray analysis made simple

      Nature Genetics
      1 March 2003

    • A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling

      Nature Biotechnology
      10 February 2003

  • Transcriptomics

    • Complete sequencing and characterization of 21,243 full-length human cDNAs

      Nature Genetics
      21 December 2003

    • Tissue microarray analyses of G1/S-regulatory proteins in ductal carcinoma in situ of the breast indicate that low cyclin D1 is associated with local recurrence

      British Journal of Cancer
      17 November 2003

    • Diagnostic and prognostic prediction using gene expression profiles in high-dimensional microarray data

      British Journal of Cancer
      3 November 2003

    • DNA microarray analysis of hematopoietic stem cell-like fractions from individuals with the M2 subtype of acute myeloid leukemia

      Leukemia
      1 October 2003

    • Parallel analysis of transcript and metabolic profiles: a new approach in systems biology

      EMBO reports
      12 September 2003

    • Genomic profiling identifies alterations in TGFbold beta signaling through loss of TGFbold beta receptor expression in human renal cell carcinogenesis and progression

      Oncogene
      11 September 2003

    • Proteomic analysis of hematopoietic stem cell-like fractions in leukemic disorders

      Oncogene
      28 August 2003

    • Genome-wide-array-based comparative genomic hybridization reveals genetic homogeneity and frequent copy number increases encompassing CCNE1 in Fallopian tube carcinoma

      Oncogene
      3 July 2003

    • DNA microarrays for comparison of gene expression profiles between diagnosis and relapse in precursor-B acute lymphoblastic leukemia: choice of technique and purification influence the identification of potential diagnostic markers

      Leukemia
      1 July 2003

    • Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer

      Oncogene
      12 June 2003

    • Expression profiling reveals off-target gene regulation by RNAi

      Nature Biotechnology
      18 May 2003

    • Genome-wide comparison of human keratinocyte and squamous cell carcinoma responses to UVB irradiation: implications for skin and epithelial cancer

      Oncogene
      15 May 2003

    • cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells

      Oncogene
      1 May 2003

    • Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases

      Oncogene
      10 April 2003

    • Characteristic sequence motifs located at the genomic breakpoints of the translocation t(X;18) in synovial sarcomas

      Oncogene
      10 April 2003

    • Genomic profiling of gastric cancer predicts lymph node status and survival

      Oncogene
      27 March 2003

    • Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays

      Oncogene
      27 February 2003

    • Scanning the human genome with combinatorial transcription factor libraries

      Nature Biotechnology
      18 February 2003

    • hTERT associates with human telomeres and enhances genomic stability and DNA repair

      Oncogene
      9 January 2003

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