Organisms - Human

  • Cancer genomics

    • Molecular portraits and the family tree of cancer

      Nature Genetics
      1 December 2002

    • Genomic instability driven by the human T-cell leukemia virus type I (HTLV-I) oncoprotein, Tax

      Oncogene
      17 October 2002

    • Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon

      Oncogene
      18 July 2002

    • Mutations of the BRAF gene in human cancer

      Nature
      9 June 2002

    • Oncogenomics: cancer and technology

      Nature Genetics
      1 June 2002

    • Genetics of chronic lymphocytic leukemia: genomic aberrations and VH gene mutation status in pathogenesis and clinical course

      Leukemia
      27 May 2002

    • Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product

      Oncogene
      16 May 2002

    • Potential involvement of the AML1-MTG8 fusion protein in the granulocytic maturation characteristic of the t(8;21) acute myelogenous leukemia revealed by microarray analysis

      Leukemia
      30 April 2002

    • Distinct genomic events in the myeloid and lymphoid lineages in simultaneous presentation of chronic myeloid leukemia and B-chronic lymphocytic leukemia

      Leukemia
      30 April 2002

    • Identification of novel targets for cancer therapy using expression proteomics

      Leukemia
      8 April 2002

    • Prediction of central nervous system embryonal tumour outcome based on gene expression

      Nature
      24 January 2002

    • Global gene expression profiling in Barrett's esophagus and esophageal cancer: a comparative analysis using cDNA microarrays

      Oncogene
      17 January 2002

  • Chemical genomics

    • Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays

      Nature
      11 April 2002

  • Comparative, evolutionary and population genomics

  • Epigenomics

    • Memory and flexibility of cytokine gene expression as separable properties of human TH1 and TH2 lymphocytes

      Nature Immunology
      25 November 2002

    • Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors

      Nature Genetics
      30 September 2002

    • A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

      Nature Genetics
      6 May 2002

    • Preparing the target for the bullet

      Nature Immunology
      1 January 2002

  • Genetics of Gene Expression

    • The genetics of variation in gene expression

      Nature Genetics
      1 December 2002

    • Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon

      Oncogene
      18 July 2002

    • Genetic Aspects of Stroke: Human and Experimental Studies

      Journal of Cerebral Blood Flow & Metabolism
      1 July 2002

    • A genome-wide linkage analysis of orchard grass-sensitive childhood seasonal allergic rhinitis in Japanese families

      Genes and Immunity
      14 February 2002

  • Genome sequence and analysis

    • Functional genomics: A time and place for every gene

      Nature
      5 December 2002

    • Numerous potentially functional but non-genic conserved sequences on human chromosome 21

      Nature
      5 December 2002

    • Chipping away at genomic medicine

      Nature Genetics
      1 December 2002

    • Medical applications of haplotype-based SNP maps: learning to walk before we run

      Nature Genetics
      1 November 2002

    • Genomic organization of classical human low-affinity Fcγ receptor genes

      Genes and Immunity
      1 October 2002

    • Genome scan stratified by the presence of anti-double-stranded DNA (dsDNA) autoantibody in pedigrees multiplex for systemic lupus erythematosus (SLE) establishes linkages at 19p13.2 (SLED1) and 18q21.1 (SLED2)

      Genes and Immunity
      1 October 2002

    • Genomics for all

      Nature Genetics
      1 October 2002

    • A genome scan for loci influencing anti-atherogenic serum bilirubin levels

      European Journal of Human Genetics
      23 August 2002

    • A genome-wide screen for linkage in Nordic sib-pairs with multiple sclerosis

      Genes and Immunity
      6 August 2002

    • Human genome sequence variation and the influence of gene history, mutation and recombination

      Nature Genetics
      5 August 2002

    • A first-generation linkage disequilibrium map of human chromosome 22

      Nature
      10 July 2002

    • A high-resolution recombination map of the human genome

      Nature Genetics
      10 June 2002

    • The Iceland map

      Nature Genetics
      10 June 2002

    • Genome duplication strikes back

      Nature Genetics
      1 June 2002

    • Extensive genomic duplication during early chordate evolution

      Nature Genetics
      28 May 2002

    • Clustering of housekeeping genes provides a unified model of gene order in the human genome

      Nature Genetics
      6 May 2002

    • Genomic organization of a novel glycosylphosphatidylinositol MAM gene expressed in human tissues and tumors

      Oncogene
      1 May 2002

    • Using the transcriptome to annotate the genome

      Nature Biotechnology
      1 May 2002

    • Strong male-driven evolution of DNA sequences in humans and apes

      Nature
      11 April 2002

    • Combined transcriptome and genome analysis of single micrometastatic cells

      Nature Biotechnology
      1 April 2002

    • The ABCs of genomics

      Nature Genetics
      1 April 2002

    • Patterns of linkage disequilibrium in the human genome

      Nature Reviews Genetics
      1 April 2002

    • Genome-wide analysis of mRNAs targeted to yeast mitochondria

      EMBO reports
      1 February 2002

    • The HGP: end of phase 1

      Nature Genetics
      1 February 2002

    • The human telomerase gene: complete genomic sequence and analysis of tandem repeat polymorphisms in intronic regions

      Oncogene
      23 January 2002

    • Identification of foreign gene sequences by transcript filtering against the human genome

      Nature Genetics
      14 January 2002

    • A genomic view of alternative splicing

      Nature Genetics
      1 January 2002

  • Metabolomics/nomics

    • Biochemical networking contributes more to genetic buffering in human and mouse metabolic pathways than does gene duplication

      Nature Genetics
      5 August 2002

  • Proteomics

    • Protein microarrays and proteomics

      Nature Genetics
      1 December 2002

    • Genetic Aspects of Stroke: Human and Experimental Studies

      Journal of Cerebral Blood Flow & Metabolism
      1 July 2002

    • Proteome analysis of nuclear matrix proteins during apoptotic chromatin condensation

      Cell Death and Differentiation
      22 May 2002

    • Synaptic multiprotein complexes associated with 5-HT2C receptors: a proteomic approach

      The EMBO Journal
      15 May 2002

    • Identification of novel targets for cancer therapy using expression proteomics

      Leukemia
      8 April 2002

    • Functional proteomics of transforming growth factor-bold beta1-stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFbold beta1-dependent regulation of DNA repair

      The EMBO Journal
      1 March 2002

  • Systems biology

  • Techniques and methods

    • Sharper tools and simpler methods

      Nature Genetics
      1 December 2002

    • Microarray databases: standards and ontologies

      Nature Genetics
      1 December 2002

    • Options available—from start to finish—for obtaining data from DNA microarrays II

      Nature Genetics
      1 December 2002

    • Fundamentals of experimental design for cDNA microarrays

      Nature Genetics
      1 December 2002

    • Microarray data normalization and transformation

      Nature Genetics
      1 December 2002

    • From patterns to pathways: gene expression data analysis comes of age

      Nature Genetics
      1 December 2002

    • Representation is faithfully preserved in global cDNA amplified exponentially from sub-picogram quantities of mRNA

      Nature Biotechnology
      12 August 2002

    • A PCR-based amplification method retaining the quantitative difference between two complex genomes

      Nature Biotechnology
      5 August 2002

    • Genomics and natural language processing

      Nature Reviews Genetics
      1 August 2002

    • Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon

      Oncogene
      18 July 2002

    • GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways

      Nature Genetics
      1 May 2002

    • Dissecting glucose signalling with diversity-oriented synthesis and small-molecule microarrays

      Nature
      11 April 2002

    • Identification of novel targets for cancer therapy using expression proteomics

      Leukemia
      8 April 2002

  • Transcriptomics

    • A molecular signature of metastasis in primary solid tumors

      Nature Genetics
      9 December 2002

    • Functional genomics: A time and place for every gene

      Nature
      5 December 2002

    • Numerous potentially functional but non-genic conserved sequences on human chromosome 21

      Nature
      5 December 2002

    • Better therapeutics through microarrays

      Nature Genetics
      1 December 2002

    • Coming to terms with microarrays

      Nature Genetics
      1 November 2002

    • The brain on microarrays

      Nature Genetics
      1 November 2002

    • Representation is faithfully preserved in global cDNA amplified exponentially from sub-picogram quantities of mRNA

      Nature Biotechnology
      12 August 2002

    • A PCR-based amplification method retaining the quantitative difference between two complex genomes

      Nature Biotechnology
      5 August 2002

    • Selection for short introns in highly expressed genes

      Nature Genetics
      22 July 2002

    • Using the transcriptome to annotate the genome

      Nature Biotechnology
      1 May 2002

    • Potential involvement of the AML1-MTG8 fusion protein in the granulocytic maturation characteristic of the t(8;21) acute myelogenous leukemia revealed by microarray analysis

      Leukemia
      30 April 2002

    • Combined transcriptome and genome analysis of single micrometastatic cells

      Nature Biotechnology
      1 April 2002

    • Prediction of central nervous system embryonal tumour outcome based on gene expression

      Nature
      24 January 2002

    • Global gene expression profiling in Barrett's esophagus and esophageal cancer: a comparative analysis using cDNA microarrays

      Oncogene
      17 January 2002

    • Identification of foreign gene sequences by transcript filtering against the human genome

      Nature Genetics
      14 January 2002

    • A genomic view of alternative splicing

      Nature Genetics
      1 January 2002

    • Preparing the target for the bullet

      Nature Immunology
      1 January 2002

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