TABLE 2
FROM:
Obesity Modulates the Association among APOE Genotype, Insulin, and Glucose in Men
Roberto Elosua, Serkalem Demissie, L. Adrienne Cupples, James B. Meigs, Peter W.F. Wilson, Ernst J. Schaefer, Dolores Corella and Jose M. Ordovas
BACK TO ARTICLETable 2. Characteristics of the population and insulin and glucose levels according to APOE genotype and stratified by sex
| Men | Women | |||||||
|---|---|---|---|---|---|---|---|---|
| APOE2 ‡ (n = 182) | APOE3 ‡ (n = 943) | APOE4 ‡ (n = 285) | p | APOE2 ‡ (n = 219) | APOE3 ‡ (n = 979) | APOE4 ‡ (n = 321) | p | |
| Age (years)* | 55.4 (10.0) | 55.1 (10.1) | 55.4 (10.1) | 0.900 | 55.6 (9.4) | 54.9 (10.1) | 54.5 (9.7) | 0.443 |
| BMI (kg/m2)* | 28.3 (4.0) | 28.2 (4.1) | 28.0 (3.8) | 0.624 | 26.7 (5.5) | 26.6 (5.4) | 27.1 (5.8) | 0.397 |
| Obesity (%) | 30.4 | 26.3 | 25.3 | 0.440 | 21.1 | 21.3 | 23.5 | 0.680 |
| Waist circumference (cm)* | 100.1 (10.9) | 99.1 (10.9) | 98.6 (10.4) | 0.289 | 87.4 (14.2) | 86.9 (14.2) | 88.1 (15.0) | 0.391 |
| Abdominal obesity (%) | 37.9 | 32.3 | 34.0 | 0.324 | 41.7 | 37.0 | 39.5 | 0.371 |
| Smoking (%) | 22.0 | 18.8 | 19.0 | 0.601 | 19.3 | 20.1 | 17.8 | 0.647 |
| Alcohol (%) | 79.1 | 75.0 | 71.6 | 0.183 | 66.2 | 63.8 | 67.2 | 0.485 |
| % Energy from SF* † | 10.9 (2.8) | 10.7 (3.0) | 10.2 (2.7) | 0.059 | 10.4 (2.7) | 10.4 (2.9) | 10.4 (2.8) | 0.888 |
| Beta-blockers (%) | 13.2 | 11.1 | 12.6 | 0.631 | 8.7 | 9.1 | 9.0 | 0.980 |
| Diuretics (%) | 7.1 | 5.5 | 4.9 | 0.581 | 8.7 | 8.5 | 8.7 | 0.990 |
| Insulin (pM)* | 31.7 (12.1) | 31.2 (12.3) | 33.7 (16.9) | 0.031 | 29.4 (13.6) | 28.1 (10.1) | 28.9 (10.4) | 0.219 |
| Glucose (mg/dL)* | 103.0 (27.3) | 100.7 (22.8) | 103.5 (27.2) | 0.152 | 95.0 (15.3) | 95.1 (15.4) | 96.6 (23.4) | 0.377 |
* Mean (SD).
† SF, saturated fat.
‡
APOE2 group includes
2/
2 and
2/
3 genotypes; APOE3 group includes
3/
3; and APOE4 group includes
3/
4 and
4/
4 genotypes.
