1
Sam Gellman is in the Department of Chemistry,
University of Wisconsin, Madison, Wisconsin
53706, USA.gellman@chem.wisc.edu
2
Dek Woolfson is in the Centre for Biomolecular
Design & Drug Development, School of Biological Sciences, University of
Sussex, Falmer, BN1 9QG,
UK.dek@biols.susx.ac.uk
A new 20-residue peptide represents the smallest example to date
of cooperatively folded tertiary structure. This achievement provides a new
tool for elucidating protein conformational preferences. The mini-protein
should serve as a fruitful platform for protein design.
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