Single-handed recognition of a sorting traffic motif by the GGA proteins
Tom Kirchhausen
Tomas Kirchhausen is in the Department of Cell Biology, Harvard Medical School and The Center for Blood Research, Boston, Massachusetts 02115, USA. kirchhausen@crystal.harvard.edu
Selective transport of cargo between membrane-bound organelles is vital for the well-being of cells. The crystal structure of a short peptide signal from the cytoplasmic tail of the mannose-6-phosphate receptor bound to the VHS domain of GGA proteins gives hints to how sorting works.
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