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Nature Structural Biology
ISSUE
January 2002, Volume 9 No 1
Editorial
News and Views
Picture Story
Letters
Articles
About the cover
Editorial Top
Designer drug, designed therapy p1
doi:10.1038/nsb0102-1
Full text | PDF (31K)
News and Views Top
Disulfides out of thin air pp2 - 3
Jean-François Collet & James C.A. Bardwell
doi:10.1038/nsb0102-2
Abstract | Full text | PDF (203K)
See also: Article by Gross et al.
Lessons from a bacterial cocaine esterase pp4 - 5
William F. Bosron & Thomas D. Hurley
doi:10.1038/nsb0102-4
Abstract | Full text | PDF (46K)
See also: Letter by Larsen et al.
Hanging on to the branch pp5 - 7
Jonathan P. Staley
doi:10.1038/nsb0102-5
Abstract | Full text | PDF (783K)
Degrading liaisons: Siah structure revealed pp8 - 10
John C. Reed & Kathryn R. Ely
doi:10.1038/nsb0102-8
Abstract | Full text | PDF (875K)
See also: Article by Polekhina et al.
Picture Story Top
A state-of-the-Arp structure p11
Julie Hollien
doi:10.1038/nsb0102-11
Full text | PDF (553K)
Letters Top
A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer pp12 - 16
Enrico L. DiGiammarino, Amanda S. Lee, Craig Cadwell, Weixing Zhang, Brian Bothner, Raul C. Ribeiro, Gerard Zambetti & Richard W. Kriwacki
Published online: 26 November 2001 | doi:10.1038/nsb730
Abstract | Full text | PDF (1,605K)
Crystal structure of a bacterial cocaine esterase pp17 - 21
Nicholas A. Larsen, James M. Turner, James Stevens, Susan J. Rosser, Amrik Basran, Richard A. Lerner, Neil C. Bruce & Ian A. Wilson
Published online: 17 December 2001 | doi:10.1038/nsb742
PDB code 1JU3 | 1JU4
Abstract | Full text | PDF (1,459K)
See also: News and Views by Bosron & Hurley
Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders pp22 - 26
Claudia Binda, Paige Newton-Vinson, Frantisek Hubálek, Dale E. Edmondson & Andrea Mattevi
Published online: 26 November 2001 | doi:10.1038/nsb732
PDB code 1GOS
Abstract | Full text | PDF (1,677K)
The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor pp27 - 31
Sergey Korolev, Yoshihiko Ikeguchi, Tatiana Skarina, Steven Beasley, Cheryl Arrowsmith, Aled Edwards, Andrzej Joachimiak, Anthony E. Pegg & Alexei Savchenko
Published online: 03 December 2001 | doi:10.1038/nsb737
PDB code 1INL | 1JQ3
Abstract | Full text | PDF (1,742K)
A unique fold of phospholipase C-beta mediates dimerization and interaction with Galphaq pp32 - 36
Alex U. Singer, Gary L. Waldo, T. Kendall Harden & John Sondek
Published online: 26 November 2001 | doi:10.1038/nsb731
PDB code 1JAD
Abstract | Full text | PDF (2,973K)
Phototransformation of green fluorescent protein with UV and visible light leads to decarboxylation of glutamate 222 pp37 - 41
Jasper J. van Thor, Thomas Gensch, Klaas J. Hellingwerf & Louise N. Johnson
Published online: 10 December 2001 | doi:10.1038/nsb739
PDB code 1HCJ
Abstract | Full text | PDF (1,080K)
Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation pp42 - 47
Nancy C. Horton, Lydia F. Dorner & John J. Perona
Published online: 17 December 2001 | doi:10.1038/nsb741
PDB code 1KC6
Abstract | Full text | PDF (2,436K)
Dramatic modulation of electron transfer in protein complexes by crosslinking pp48 - 52
Irene M. C. van Amsterdam, Marcellus Ubbink, Oliver Einsle, Albrecht Messerschmidt, Angelo Merli, Davide Cavazzini, Gian Luigi Rossi & Gerard W. Canters
Published online: 10 December 2001 | doi:10.1038/nsb736
PDB code 1JVO | 1JVL
Abstract | Full text | PDF (2,270K)
Domain alternation switches B12-dependent methionine synthase to the activation conformation pp53 - 56
Vahe Bandarian, Katherine A. Pattridge, Brett W. Lennon, Donald P. Huddler, Rowena G. Matthews & Martha L. Ludwig
Published online: 03 December 2001 | doi:10.1038/nsb738
PDB code 1K7Y | 1K98
Abstract | Full text | PDF (1,577K)
The antimalarial and cytotoxic drug cryptolepine intercalates into DNA at cytosine-cytosine sites pp57 - 60
John N. Lisgarten, Miquel Coll, Jose Portugal, Colin W. Wright & Juan Aymami
Published online: 03 December 2001 | doi:10.1038/nsb729
PDB code 1K9G
Abstract | Full text | PDF (1,171K)
Articles Top
A new FAD-binding fold and intersubunit disulfide shuttle in the thiol oxidase Erv2p pp61 - 67
Einav Gross, Carolyn S. Sevier, Andrea Vala, Chris A. Kaiser & Deborah Fass
Published online: 10 December 2001 | doi:10.1038/nsb740
PDB code 1JR8 | 1JRA
Abstract | Full text | PDF (2,276K)
See also: News and Views by Collet & Bardwell
Siah ubiquitin ligase is structurally related to TRAF and modulates TNF-alpha signaling pp68 - 75
Galina Polekhina, Colin M. House, Nadia Traficante, Joel P. Mackay, Frédéric Relaix, David A. Sassoon, Michael W. Parker & David D.L. Bowtell
Published online: 17 December 2001 | doi:10.1038/nsb743
PDB code 1K2F
Abstract | Full text | PDF (1,834K)
See also: News and Views by Reed & Ely
  Top
 
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