A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramerpp12 - 16 Enrico L. DiGiammarino, Amanda S. Lee, Craig Cadwell, Weixing Zhang, Brian Bothner, Raul C. Ribeiro, Gerard Zambetti
& Richard W. Kriwacki Published online: 26 November 2001|doi:10.1038/nsb730 Abstract|Full text|PDF
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Crystal structure of a bacterial cocaine esterasepp17 - 21 Nicholas A. Larsen, James M. Turner, James Stevens, Susan J. Rosser, Amrik Basran, Richard A. Lerner, Neil C. Bruce
& Ian A. Wilson Published online: 17 December 2001|doi:10.1038/nsb742 PDB code 1JU3|1JU4 Abstract|Full text|PDF
(1,459K)
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Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorderspp22 - 26 Claudia Binda, Paige Newton-Vinson, Frantisek Hubálek, Dale E. Edmondson
& Andrea Mattevi Published online: 26 November 2001|doi:10.1038/nsb732 PDB code 1GOS Abstract|Full text|PDF
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The crystal structure of spermidine synthase with a multisubstrate adduct inhibitorpp27 - 31 Sergey Korolev, Yoshihiko Ikeguchi, Tatiana Skarina, Steven Beasley, Cheryl Arrowsmith, Aled Edwards, Andrzej Joachimiak, Anthony E. Pegg
& Alexei Savchenko Published online: 03 December 2001|doi:10.1038/nsb737 PDB code 1INL|1JQ3 Abstract|Full text|PDF
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A unique fold of phospholipase C- mediates dimerization and interaction with Gqpp32 - 36 Alex U. Singer, Gary L. Waldo, T. Kendall Harden
& John Sondek Published online: 26 November 2001|doi:10.1038/nsb731 PDB code 1JAD Abstract|Full text|PDF
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Phototransformation of green fluorescent protein with UV and visible light leads to decarboxylation of glutamate 222pp37 - 41 Jasper J. van Thor, Thomas Gensch, Klaas J. Hellingwerf
& Louise N. Johnson Published online: 10 December 2001|doi:10.1038/nsb739 PDB code 1HCJ Abstract|Full text|PDF
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Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalationpp42 - 47 Nancy C. Horton, Lydia F. Dorner
& John J. Perona Published online: 17 December 2001|doi:10.1038/nsb741 PDB code 1KC6 Abstract|Full text|PDF
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Dramatic modulation of electron transfer in protein complexes by crosslinkingpp48 - 52 Irene M. C. van Amsterdam, Marcellus Ubbink, Oliver Einsle, Albrecht Messerschmidt, Angelo Merli, Davide Cavazzini, Gian Luigi Rossi
& Gerard W. Canters Published online: 10 December 2001|doi:10.1038/nsb736 PDB code 1JVO|1JVL Abstract|Full text|PDF
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Domain alternation switches B12-dependent methionine synthase to the activation conformationpp53 - 56 Vahe Bandarian, Katherine A. Pattridge, Brett W. Lennon, Donald P. Huddler, Rowena G. Matthews
& Martha L. Ludwig Published online: 03 December 2001|doi:10.1038/nsb738 PDB code 1K7Y|1K98 Abstract|Full text|PDF
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The antimalarial and cytotoxic drug cryptolepine intercalates into DNA at cytosine-cytosine sitespp57 - 60 John N. Lisgarten, Miquel Coll, Jose Portugal, Colin W. Wright
& Juan Aymami Published online: 03 December 2001|doi:10.1038/nsb729 PDB code 1K9G Abstract|Full text|PDF
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A new FAD-binding fold and intersubunit disulfide shuttle in the thiol oxidase Erv2ppp61 - 67 Einav Gross, Carolyn S. Sevier, Andrea Vala, Chris A. Kaiser
& Deborah Fass Published online: 10 December 2001|doi:10.1038/nsb740 PDB code 1JR8|1JRA Abstract|Full text|PDF
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Siah ubiquitin ligase is structurally related to TRAF and modulates TNF- signalingpp68 - 75 Galina Polekhina, Colin M. House, Nadia Traficante, Joel P. Mackay, Frédéric Relaix, David A. Sassoon, Michael W. Parker
& David D.L. Bowtell Published online: 17 December 2001|doi:10.1038/nsb743 PDB code 1K2F Abstract|Full text|PDF
(1,834K)
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