Marcia E. Newcomer is at Vanderbilt University, School of Medicine, Department of Biochemistry, Nashville, Tennessee 37232, USA.newcomer@lhmrba.hh.vanderbilt.edu
Protein polymerization via 3D domain swapping has been suggested to promote amyloid plaque formation. Two recent papers provide support for a role for domain swapping in the formation of highly ordered aggregates such as the fibrils characteristic of amyloid plaques.
