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Nature Structural Biology  8, 101 - 103 (2001)
doi:10.1038/84072

A Taq attack displaces bases

Robert M. Blumenthal1 & Xiaodong Cheng2

1  Robert M. Blumenthal is in the Department of Microbiology and Immunology, Medical College of Ohio, 3055 Arlington Avenue, Toledo, Ohio 43614-5806, USA

2  Xiaodong Cheng is in the Department of Biochemistry, Emory University School of Medicine, 1510 Clifton Road, Atlanta, Georgia 30322, USA.

Correspondence should be addressed to Robert M. Blumenthal rblumenthal@mco.edu or Xiaodong Cheng xcheng@emory.edu
The cocrystal structure of TaqI DNA methyltransferase in complex with its specific DNA substrate adds to the growing list of structurally confirmed DNA base-flipping enzymes, and provides a basis for the general mechanism of AdoMet-dependent DNA N-methylation.

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Nature Structural & Molecular Biology
ISSN: 1545-9993
EISSN: 1545-9985
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