Converging on proline: the mechanism of WW domain peptide recognition
Ali Zarrinpar
& Wendell A. Lim
Ali Zarrinpar and Wendell A. Lim are in the Department of Cellular and Molecular Pharmacology, Department of Biochemistry and Biophysics, and Program in Biological Sciences, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, California 94143-0450, USA.
Two new structures reveal the general rules of proline-rich motif recognition by WW domains and show that they are strikingly similar to those used by SH3 domains.