C. Nick Pace is in the Department of Medical Biochemistry
& Genetics, Texas A&M University, College Station,
Texas 77845-1114, USA. nickpace@tamu.edu
The enhanced stability of a cold shock protein from a thermophilic
organism, compared to its counterpart from a mesophile, results mainly from
a single change in amino acid sequence that improves electrostatic interactions
among the charged groups on the protein surface.
