Nature Structural Biology
7, 97 - 99 (2000)
doi:10.1038/72464
Are DEAD-box proteins becoming respectable helicases?Patrick Linder1
& Marie-Claire Daugeron21
Patrick Linder is in the Dépt. de Biochimie médicale CMU, 1, rue Michel Servet, Genève 4, 1211, Switzerland
2
Marie-Claire Daugeron is in the Inst. de Génétique et Microbiologie, Bâtiment 400 URA 2225, Université Paris-Sud, 91405 Orsay Cedex, France.
Correspondence should be addressed to Patrick Linder Patrick.Linder@medecine.unige.chThe vaccinia NPH-II RNA helicase, a member of the DEAD/DExH-box protein family, has been shown to be a processive, unidirectional RNA helicase with a step size of about one half turn of a helix. This finding demonstrates that RNA helicases can function as molecular motors.
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