Ming-Ming Zhou is in the Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, 1425 Madison Avenue, Box 1677, New York, New York 10029, USA. zhoum@inka.mssm.edu
The structure of the Rad53p FHA domain reveals a new fundamental mechanism governing phosphothreonine-dependent protein−protein interactions in nuclear processes including DNA repair and replication in a broad range of organisms.