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Nature Structural Biology  6, 1081 - 1083 (1999)
doi:10.1038/70002

If the loop fits...

Alan D. Frankel

Alan D. Frankel is in the Department of Biochemistry and Biophysics, University of California San Francisco, 513 Parnassus Avenue, San Francisco, California 94143-0448, USA. frankel@cgl.ucsf.edu

The structure of the yeast L30 ribosomal protein bound to its autoregulatory RNA site has been determined by NMR spectroscopy. The intricate architecture of the RNA internal loop and the structure of the binding region of the protein both are stabilized in the complex, highlighting the importance of mutually-induced fit in RNA−protein interactions.

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Nature Structural & Molecular Biology
ISSN: 1545-9993
EISSN: 1545-9985
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