Structural genomics: keystone for a Human Proteome Project
Gaetano T. Montelione
& Stephen Anderson
Gaetano Montelione and Stephen Anderson are in the Center for Advanced
Biotechnology and Medicine and Department of Molecular Biology and Biochemisty,
Rutgers University, Piscataway New Jersey
08854-5638, USA. guy@nmrlab.cabm.rutgers.edu or anderson@mbcl.rutgers.edu
A natural extension of the genome sequencing projects involves analysis
of the corresponding three dimensional protein structures. This emerging field
of 'structural genomics' has the potential to unify our understanding of the
structural basis of protein function.