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Journal home Advance online publication Current issue Archive Press releases Supplements Focus Guide to authors Online submission Permissions For referees Free online issue Contact the journal Subscribe Advertising work@npg naturereprints About this site For librarians   NPG Resources Nature Nature Cell Biology Nature Reviews Molecular Cell Biology The EMBO Journal Nature Reports Stem Cells Nature Reports Avian Flu NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Nature Structural Biology  5, 412 - 414 (1998) doi:10.1038/nsb0698-412 Imperfect interfaces Xavier Ysern1, Hongmin Li2 & Roy A. Mariuzza2, 3   1Xavier Ysern is in the Center for Drug Evaluation and Research,United States Food and Drug Administration, 5600 Fishers Lane, Rockville, Maryland 20857, USA.   2Hongmin Li and Roy A. Mariuzza is in the Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, Maryland 20850, USA.   3e-mail: mariuzza@indigo2.carb.nist.gov The crystal structure of a T cell receptor bound to a self peptide−major histocompatibility complex antigen reveals poor shape complementarity in the interface between the two proteins, as well as large conformational changes in the T cell receptor combining site upon ligand binding.  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Save this link Open Innovation Challenges Mitigating Zinc Corrosion Deadline: Aug 23 2009 Reward: $20,000 USD The Seeker is looking for novel methods to mitigate zinc corrosion/gassing in alkaline media. This ... Fast Growth of Transformed Soybean Shoots Deadline: Jul 15 2009 Reward: $10,000 USD A method for accelerating growth of soybean shoots is desired. More Challenges Powered by: nature jobs Scientist, Recombinant Protein Expression Novo Nordisk Foundation Center for Protein Research, University of Copenhagen Copenhagen 2200 Denmark Assistant or Associate Professor Texas Tech University Health Sciences Center Lubbock, TX United States More science jobs Post a job for free Export citation Search buyers guide:   ADVERTISEMENT

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