Journal home
Advance online publication
Current issue
Archive
Press releases
Supplements
Focus
Guide to authors
Online submissionOnline submission
Permissions
For referees
Free online issue
Contact the journal
Subscribe
Advertising
work@npg
naturereprints
About this site
For librarians
 
NPG Resources
Nature
Nature Cell Biology
Nature Reviews Molecular Cell Biology
The EMBO Journal
Nature Reports Stem Cells
Nature Reports Avian Flu
NPG Subject areas
Biotechnology
Cancer
Chemistry
Clinical Medicine
Dentistry
Development
Drug Discovery
Earth Sciences
Evolution & Ecology
Genetics
Immunology
Materials Science
Medical Research
Microbiology
Molecular Cell Biology
Neuroscience
Pharmacology
Physics
Browse all publications
News and Views
Nature Structural Biology  5, 412 - 414 (1998)
doi:10.1038/nsb0698-412

Imperfect interfaces

Xavier Ysern1, Hongmin Li2 & Roy A. Mariuzza2, 3

  1Xavier Ysern is in the Center for Drug Evaluation and Research,United States Food and Drug Administration, 5600 Fishers Lane, Rockville, Maryland 20857, USA.

  2Hongmin Li and Roy A. Mariuzza is in the Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, 9600 Gudelsky Drive, Rockville, Maryland 20850, USA.

  3e-mail: mariuzza@indigo2.carb.nist.gov

The crystal structure of a T cell receptor bound to a self peptide−major histocompatibility complex antigen reveals poor shape complementarity in the interface between the two proteins, as well as large conformational changes in the T cell receptor combining site upon ligand binding.

 Top
Abstract
Previous | Next
Table of contents
Full textFull text
Download PDFDownload PDF
Send to a friendSend to a friend
Save this linkSave this link

Open Innovation Challenges

naturejobs

Export citation
natureproducts

Search buyers guide:

 
ADVERTISEMENT
 
Nature Structural & Molecular Biology
ISSN: 1545-9993
EISSN: 1545-9985
Journal home | Advance online publication | Current issue | Archive | Press releases | Supplements | For authors | Online submission | Permissions | For referees | Free online issue | About the journal | Contact the journal | Subscribe | Advertising | work@npg | naturereprints | About this site | For librarians
Nature Publishing Group, publisher of Nature, and other science journals and reference works©1998 Nature Publishing Group | Privacy policy