1Kathryn R. Ely and Ramadurgam Kodandapani are at the Cancer Research Center, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, California 92037 USA.
2email: ely@burnham-inst.org
The crystal structure of the heterodimeric transcriptional regulator GABP/ bound to DNA reveals extensive protein−protein interactions between an ETS domain and ankyrin repeats that may influence DNA binding affinity.