Nature Structural Biology
5, 843 - 845 (1998)
doi:10.1038/2283
A flattened face for membranesChristopher L. Carpenter
& Lewis C. Cantley
Departments of Medicine and Cell Biology, Harvard Medical School and Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.
Correspondence should be addressed to Christopher L. Carpenter ccarpent@bidmc.harvard.eduThe solution of the crystal structure of a phosphatidylinositol phosphate kinase has shown it to have a tertiary structure much like protein kinases, but with a flattened face that likely allows it to dock onto membranes.
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