1
Departments of Biochemistry and Pharmacology, the Center for Basic Neuroscience and the Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75235, USA.
2
Department of Molecular Genetics, the Center for Basic Neuroscience and the Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75235, USA.
A fascinating problem in modern cell biology how membranes fuse
may be close to a solution. A flurry of recent papers report structural
results on proteins that are essential for membrane fusion during exocytosis,
providing a starting point from which a mechanistic understanding of membrane
fusion can be launched.