1Duncan E. McRee is in the department of Molecular Biology, MB8, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, California 92037, USA. email: dem@scripps.edu
The NMR structure of a copper-binding domain of the protein responsible for Menkes' syndrome demonstrates that the Cys-xx-Cys motif is used by prokaryotes and eukaryotes to deal with heavy metals.
